BACKGROUND Contact allergy epidemics to chromate and nickel were addressed in Denmark in 1983 and 1990 by regulatory interventions. OBJECTIVES To evaluate whether regulatory interventions on nickel and chromate exposure have reduced the proportion of strong patch test reactions. METHODS 22 506 patients with dermatitis aged 4-99 years were patch tested with nickel sulfate, potassium dichroma...

BACKGROUND Nickel in metallic items has been regulated in Denmark since 1990; however, 10% of young Danish women are still sensitized to nickel. There is a need for continuous surveillance of the effect of regulation. OBJECTIVES To identify current self-reported metallic exposures leading to dermatitis in nickel-allergic patients, and the minimum contact time needed for dermatitis to occur. ...

STUDY OBJECTIVE To review reported adverse events associated with suspected nickel hypersensitivity and subsequent clinical outcomes in patients with Essure implants and to evaluate the correlation of nickel allergy-related adverse events with positive results of nickel patch testing. DESIGN Case series (Canadian Task Force classification II-3). MEASUREMENTS AND MAIN RESULTS Reports of susp...

is more common in women than in men. Conclusions: Approximately 25 chemicals appear to be responsible for as many as one half of all cases of allergic contact dermatitis. These include nickel, preservatives, dyes, and fragrances. in this study Allergic contact dermatitis is more common in women than in men. This predominantly is a result of allergy to nickel, which is much more common in women ...

is more common in women than in men. Conclusions: Approximately 25 chemicals appear to be responsible for as many as one half of all cases of allergic contact dermatitis. These include nickel, preservatives, dyes, and fragrances. in this study Allergic contact dermatitis is more common in women than in men. This predominantly is a result of allergy to nickel, which is much more common in women ...

Nickel sensitized patients may suffer of contact dermatitis,but also of urticaria-like, pruritus-erythema and cutaneous rush,sometimes associated with intestinal symptoms.The role of Nickel absorption due to food is still debated, but a clinical framework of Systemic Nickel Allergy Syndrome (SNAS) may be proposed, while a possible induction of oral tolerance deserves to be investigated. In the ...

The issue of transcatheter heart valve (THV) thrombosis is a poorly understood emerging entity of great clinical importance. There are now a number of papers describing both clinically apparent and silent THV thrombosis (1). The literature describes a very heterogenous cohort in terms of the timing of presentation (2 days to 24 months); however, the dominant mode of presentation is recurrent dy...

BACKGROUND Monitoring trends of positive patch test reactions is useful for epidemiological surveillance and contact allergy prevention, and has not previously been reported in Lithuania. OBJECTIVES To examine and compare changes in the prevalence of contact allergy to European baseline series allergens in adults with suspected contact dermatitis during a 9-year period. METHODS In this retr...

The problems in patch testing and relevance evaluation as well as the practical consequences are discussed for the most important groups of dental materials (DM). These include metal alloys: amalgam with a low allergy prevalence; palladium salts showing a high correlation with nickel allergy but a low one with metallic palladium or alloys; the widespread allergen nickel is most relevant when de...

BACKGROUND Several studies have shown a high incidence of metal allergy after minimally-invasive repair of pectus excavatum (MIRPE). We postulated that MIRPE is associated with a significant release of trace metal ions, possibly causing the allergic symptoms. METHODS We evaluated the concentration with chromium, cobalt and nickel in blood, urine and tissue in patients prior to MIRPE and in pa...