نتایج جستجو برای: michaelis
تعداد نتایج: 4315 فیلتر نتایج به سال:
Seychelles Creole (SC) is one of the few creoles with a grammaticalized reciprocity marker. The use kanmarad (< Fr. camarade ‘comrade, companion’) mentioned in grammars SC (Bollée 1977; Corne Choppy 2009) but its evolution and distribution modern have never been analyzed. This contribution first presents present-day data from spoken written corpora compares them to published Atlas Pidgin Lan...
Malakoplakia is a rare disease with undefined etiology that has been almost exclusively reported in urology and pathology journals. We are presenting a case of colonic malakoplakia in an I8-year old young man who was referred to us with a four-year history of intermittent rectorrhagia. The pathological examination of the endoscopically resected specimen revealed pathognomonic features of ma...
Enzymes are biological catalysts vital to life processes and have attracted century-long investigation. The classic Michaelis-Menten mechanism provides a highly satisfactory description of catalytic activities for large ensembles of enzyme molecules. Here we tested the Michaelis-Menten equation at the single-molecule level. We monitored long time traces of enzymatic turnovers for individual b-g...
How an enzyme activates its substrate for turnover is fundamental for catalysis but incompletely understood on a structural level. With redox enzymes one typically analyses structures of enzyme–substrate complexes in the unreactive oxidation state of the cofactor, assuming that the interaction between enzyme and substrate is independent of the cofactors oxidation state. Here, we investigate the...
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