Objective(s): With the advent of nanotechnology, significant progress has been made in the area of nanoscale materials such as nanosilver (Ag-Nps). These nanoparticles have a wide range of applications and been used for antimicrobial purposes for more than a century. However, little attention has been paid to the toxicity of nanosilver wound dressing. This study was designed to investigate the ...

Arnebia euchroma is from Boraginaceae family. Various therapeutic effects have been reported for different species of this plant. The aim of this study was to investigate antioxidant activity of hydroalcoholic extract of the root of A. euchroma and its protective effect on hepatotoxicity induced by CCl4 in mice. In this experimental study, A. euchroma was extracted with ethanol solvent by macer...

Background: This study was carried out to observe the radioprotective effects of Rosemarinus officinalis leaves extract (ROE) against radiation-induced histopathological alterations in liver of mice. Materials and Methods: Adult Swiss albino mice were exposed to 6 Gy gamma radiation in the presence (experimental) or absence (control) of ROE to study the qualitative and quantitative alt...

Objectives: The natural origin of medicinal plants does not guaranteed their safety, as there are no sufficient studies on the safety, efficacy and toxicity to support their beneficial claims. Hence, this study aimed at investigating the oral acute toxicity of Adansonia digitata L. fruit shell extract on mice. Methods: Maceration method was employed for the extraction of Adansonia digitata fru...

objective(s): with the advent of nanotechnology, significant progress has been made in the area of nanoscale materials such as nanosilver (ag-nps). these nanoparticles have a wide range of applications and been used for antimicrobial purposes for more than a century. however, little attention has been paid to the toxicity of nanosilver wound dressing. this study was designed to investigate the ...

The Breast Cancer Resistance Protein (BCRP/ABCG2) is an ATP-binding cassette efflux transporter that expressed in the apical membrane of cells from relevant tissues involved drug pharmacokinetics such as liver, intestine, kidney, testis, brain and mammary gland, among others. Tolfenamic acid anti-inflammatory used analgesic antipyretic humans animals. Recently, tolfenamic has been repurposed an...