formate accumulation in blood, Formaldehyde was not measurable in an y fluids or tissu e. Experiments were designed to study the possible role of formate in ocular toxicity. Formate was administered by iv infusion in the form of formate b uffer for the purpose of maintaining pH in the normal range. The rate of formate infusion was adi ted to maintain blood formate at toxic concentration. No for...

background: it is introduced that unintentional childhood poisoning can be as result of child home environment and characteristics of parents. this study aimed at quantifying the adjusted population attributable risk percentage of risk factor of unintentional childhood poisoning.  materials and methods: the hospital based case- control included 140 consecutive poisoned children who admitted to ...

THE GUIDELINES FOR MANAGEMENT OF ETHANOL, METHANOL AND ETHYLENE GLYCOL POISONING AT THE EMERGENCY ROOM By Niru Prasad, M.D., F.A.A.P., F.A.C.E.P. Department of Emergency Medicine Henry Ford Hospital West Bloomfield Center Department of Ambulatory Pediatrics St. Joseph Mercy Hospital Pontiac Ethanol Overdose Introduction Pharmacokinetics Absorption and Metabolism Clinical Symptoms Produced by Et...

A case of homicidal poisoning of a 21-month-old child using methanol is presented. The child was found dead in his crib during a court-ordered visit to his father's home. He reportedly was experiencing "flu-like" symptoms the day before. Routine toxicology testing of specimens taken at autopsy revealed the presence of methanol in a concentration of 0.21%, 0.23%, 0.31%, 0.28%, and 0.26% (w/v or ...

Poisoning is an uncommon but potentially fatal outcome of toxic alcohol ingestion. The toxic alcohols methanol, ethylene glycol and isopropyl alcohol are commonly found in household and commercial products. Because the toxic effects are caused by the metabolites of methanol and ethylene glycol rather than the agents themselves, there is often a substantial delay between ingestion and onset of c...

The National Toxicology Program (NTP) Center for the Evaluation of Risks to Human Reproduction (CERHR) conducted an evaluation of the potential for methanol to cause adverse effects on reproduction and development in humans. Methanol was selected for evaluation because it is a high production volume chemical with high potential for occupational, consumer, and environmental exposure. Methanol is...

OBJECTIVES We report the results of the visual evoked potentials (VEP) examination in patients after severe poisoning by methanol. MATERIAL AND METHODS The group of 47 patients (38 males and 9 females) was assembled out of persons who survived an outbreak of poisoning by the methanol adulterated alcohol beverages, which happened in the Czech Republic in 2012-2013. The visual evoked potentials...

We report a rare case of optic nerve atrophy with severe disc cupping resulting from methanol poisoning. A 30-year-old man presented to the hospital complaining of decreased visual acuity in both eyes a day after drinking alcohol containing methanol. His initial visual acuity allowed for only visualizing hand motion and not corrected in either eye. Initial intraocular pressure was within normal...