Ménière's disease is defined as an idiopathic syndrome characterized by endolymphatic hydrops. Various tests and measurement methods have been employed for the diagnosis of Ménière's disease. These include audiological, vestibular, radiological, clinical, and biochemical tests. However, the lack of a definitive or gold standard diagnostic test sometimes complicates the process of diagnosis. Hen...

OBJECTIVE To describe the development of a new clinically applicable method for assessing vestibular function in humans with particular application in Meniere's disease. STUDY DESIGN Sophisticated signal-processing techniques were applied to data from human subject undergoing tilts stimulating the otolith organs and semicircular canals. The most sensitive representatives of vestibular functio...

Although double-blind experimental designs are considered the gold standard for documenting treatment effectiveness, many treatments for Ménière's disease have not been evaluated using this methodology. Particularly with a disease characterized by exacerbation and remission, carefully controlled, long-term studies are required. The nature of the placebo effect is described in this article, and ...

This paper explores in what circumstances patent owners can be expected to join unilaterally a patent pool. We develop a simple model in which owners of patents reading on a standard grant licences to competing manufacturers. Manufacturers must sink a …xed cost to enter the market for standard compliant products, and are thus exposed to a hold up when royalties are set after their entry. We sho...

AIM To point out the similarity of Meniere disease and spontaneous intracranial hypotension and difference of their treatment. METHODS A case of a 54-year-old male patient with previously diagnosed Meniere's disease and newly diagnosed spontaneous intracranial hypotension syndrome is presented. Additional neuroradiological examination, Brain contrast-enhanced MRI and MR myelography were used ...

Materials and Methods: This prospective study included three groups, 38 patients with Meniere’s disease (41 ears), 30 patients with cochlear hearing loss other than Meniere’s disease (40 ears) and 25 healthy subjects (40 ears). Tympanic membrane ECoG (click and tone-burst evoked) and caloric test were performed. Forty one ears with Meniere’s disease were categorized into definite (28 ears) and ...