An optimal test does not exist for the problem of detecting a known target with unknown location in additive Gaussian noise. A common solution uses a generalised likelihood ratio testing (GLRT) formalism, where a maximum likelihood estimate of the unknown location parameter is used in a likelihood ratio test. The performance of this test is commonly assessed by comparing it to the ideal matched...

The aim of this study is to determine the speech characteristics of 20 patients with Alzheimer’s disease (AD) in comparison with those of 20 age, sex, and socio-economic matched healthy controls. The first research is designed to study temporal organization of speech in the context of normal and pathological cognitive aging, and in the evolution of Alzheimer dementia using five variables: Verba...

While the left hemispheric role in speech production has been extensively studied the role of the right hemisphere is less explored. Therefore, this paper addressed the question to what extend the right hemisphere is involved in prosodic production in an intonational language such as German. In particular, we explored the speech production of three patients with right hemisphere damage and comp...