نتایج جستجو برای: male mice

تعداد نتایج: 694939  

ژورنال: مجله دانشگاه علوم پزشکی شهید صدوقی یزد 2017
ابوذری پور, مرتضی, دانشی, عرفان, روشنگر, لیلا, سلیمانی راد, جعفر,

Introduction: Tamoxifen is steroidal drug, which mainly treats breast cancer and also used to stimulate ovulation. The purpose of the present study was the evaluation of sperm parameters and fertility of mice whose mothers had received tamoxifen during pregnancy. Methods: In this study, 30 female and 15 male mice of NMRI were selected for mating. After mating female mice were randomly divide...

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ژورنال: مجله دانشگاه علوم پزشکی شهید صدوقی یزد 2016
جمالو, فاطمه, حیدریه, نسرین, عزیزی, سمیه,

Introduction: Epilepsy is a central nervous system disorder that appears as sudden convulsions, and transient, repetitive and unpredictable movement, with sensory-motor and autonomic sources. Statins are a group of blood cholesterol-lowering drugs. According to the results of the anti-inflammatory and vasoprotective effects of statins on cultured brain cells (astrocytes and microglia) and endot...

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Journal: Iranian Journal of Basic Medical Sciences 2019
Bin Zhou, Chao Ji, Fubiao Ji, Jian Ji, Manhong Ye, Mengmeng Ding, Mengting XU, Shengmei Yang, Wanhong Wei,

Objective(s): The current study investigated the potential hepatoprotective effects of the ethanolic extracts of Chinese propolis (EECP) on ethanol-induced fatty liver in mice.Materials and Methods: C57BL/6J mice were orally gavaged with 50% ethanol alone or co-administrated with EECP at the dose of 0.2 ml/kg bodyweight for eight weeks. ...

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Journal: :Journal of Immunology 2023

Abstract Sex is a significant contributor to the outcome of human infections. Males are frequently more susceptible viral, bacterial, and fungal infections, often attributed weaker immune responses. In contrast, heightened response in females enables better pathogen elimination but leaves predisposed autoimmune diseases. Unfortunately, underlying basis for sex-specific responses remains poorly ...

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Journal: :The American journal of physiology 1998
Lisa R Leon Andrew A White Matthew J Kluger

Interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) have been implicated as key mediators in inflammation, morbidity, and mortality associated with sepsis. We examined the role of IL-6 and TNF-α signaling on hypothermia, fever, cachexia, anorexia, and survival during sepsis induced by cecal ligation and puncture (CLP) in male and female gene knockout mice. Male wild-type mice developed an ...

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Journal: International Journal of Fertility and Sterility 2015
S Hoyer-Fender,

Background According to a worldwide survey in 2010 infertility affects 48.5 million of couples. In roughly half of the cases infertility is provoked by the male mate. Thus, a significant percentage of young men are infertile but the underlying causes are mostly unknown. Male fertility and reproduction success critically depends on proper formation of the mature sperm. Transmission of the geneti...

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Journal: :International journal of sciences 2023

Male patients with NPC1 heterozygous mutation (Npc1+/-) are prone to obesity and diabetes, yet the mechanism remains unclear. In this study, male Npc1+/- mice (C57BL/6C-Npc1) were used evaluate effects of combined 60% high-fat diet (HFD) on glucolipid metabolism, cholesterol accumulation, islet dysfunction β-cell dedifferentiation. Compared HFD-Npc1+/+ or fed low-fat (LFD), body weight HFD-Npc1...

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Journal: Journal of Kerman University of Medical Sciences 2018
abdolreza babaee, Ahmad Hosseini Massood Ezzatabadipour, Seyed Noureddin Nematollahi-mahani,

In this report, a rare case of pregnancy in a mouse without mating and during breastfeeding is presented. Out-bred NMRI mice were prepared for mating. Two female mice without superovulation were caged with one male. The next morning, vaginal plaque was not detected; therefore, females were kept in the cage with the same male for 4 more days. One of the females delivered 4 offspring: one female ...

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ژورنال: کومش 2021
fallahzadeh, Ali reza, Mohammadi, Saeed,

Introduction: In Iranian traditional medicine, Asparagus persicus has been used for treating rheumatic pain and inflammation. The aim of this study was to evaluate the analgesic and anti-inflammatory as well as acute toxicity effects of Asparagus persicus root essential oil (APEO) in male mice. Materials and Methods: Male adult mice were used. In pain assessment tests (writhing, tail-flick, and...

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Journal: :BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains 2022

This study aimed to analyze the effect of stem extract yellow root plant (Arcangelisia flava Merr.) from Enggano Island on introduction and locomotor activity male female mice (Mus musculus L.). The method used is an experiment with a completely randomized design. treatment variations were extracted at dose 150 mg/kgBW, 200 mg/kgBW 250 Neo Hormoviton capsules as positive control, without or str...

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