The prediction of leaf appearance rate (LAR) is an important part of many crop simulation models. Most wheat simulations models assume that LAR is affected by temperature and photoperiod. This assumption ignores the fact that seed reserves contribute to a greater LAR of the first two leaves and that the LAR of subsequent leaves decreases as a result of an increase in the distance that each leaf...

OBJECTIVES Octreotide long acting repeatable (LAR) is commonly used to control the symptoms of patients with functional neuroendocrine tumors. Unfortunately, most patients escape control over time and require higher LAR doses or more frequent rescue therapy to remain asymptomatic. Previous work has shown that body weight and monthly LAR dose will significantly affect circulating plasma octreoti...

Transanal total mesorectal excision (TaTME) is a new and promising approach for the treatment of rectal cancer. Whilst the experience is still limited, there are growing evidences that this approach might overcome the limits of standard low anterior resection. TaTME might help to decrease the conversion rate especially in difficult patients, and to improve the pathological results, while preser...

Received: 26 November 2009, Accepted: 6 February 2010 Corresponding author: Kwang-Won Kim Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, Korea Tel: +82-2-3410-3430, Fax: +82-2-3410-6956, E-mail: [email protected] Sustained Maintenance of Normal Insulin-like Growth Facto...

BACKGROUND Long-acting somatostatin analogues delivered parenterally are the most widely used medical treatment in acromegaly. This patient-reported outcomes survey was designed to assess the impact of chronic injections on subjects with acromegaly. METHODS The survey was conducted in nine pituitary centres in Germany, UK and The Netherlands. The questionnaire was developed by endocrinologist...

Efron, Hastie, Johnstone and Tibshirani (2004) proposed Least Angle Regression (LAR), a solution path algorithm for the least squares regression. They pointed out that a slight modification of the LAR gives the LASSO (Tibshirani, 1996) solution path. However it is largely unknown how to extend this solution path algorithm to models beyond the least squares regression. In this work, we propose a...

To study whether circadian variation of bronchial caliber participates in causing late asthmatic response (LAR), house-dust inhalation was made at 10 AM and 6 PM on separate days in 6 house-dust-sensitive asthmatic children aged 8 to 13 years. Bronchial obstruction was assessed through measurements of FEV1 at 4-h intervals from 24 h before to 24 h after the inhalation. The LAR, which is a 15 pe...

Objective: Octreotide is used to treat patients with neuroendocrine tumors. Previous reports show that octreotide long-acting repeatable (LAR) dose and patient body weight affect nadir plasma octreotide levels (approximately 1250, 2500, 5000, and 11,000 pg/mL for LAR doses of 10, 20, 30 and 60 mg/mo). However, plasma octreotide levels have decreased over time in patients receiving these doses o...

We discuss the possibility of new generation neutrino and astroparticle physics experiments exploiting a super-conducting magnetized liquid Argon Time Projection Chamber (LAr TPC). The possibility to complement the features of the LAr TPC with those provided by a magnetic field has been considered in the past and has been shown to open new physics opportunities, in particular in the context of ...

Materials and methods We have evaluated 69 consecutive patients (39 male and 30 female) operated for rectal cancer in our ward. The preoperative investigation includes, according to guidelines for CRC treatment: pancolonscopy, chest radiography and a CT scan of the abdomen. The most appropriate surgical treatment was chosen depending on the results of the preoperative study (Table 1). A standar...