background oral administration of pro- and prebiotics has recently been considered as an effective way for nonalcoholic fatty liver disease (nafld) recovery. objectives the current study aimed at evaluating the effect of supplementation with probiotics and/or prebiotics on liver function tests in patients with nafld. methods in this double blind, placebo-control clinical trial, 75 subjects with...

Due to their abundant nutrition and potential prebiotic functions, the potential development of oligosaccharide synthesis is very important. In this context, Synergistic catalytic manner of recombinant dextransucrase and Hypocrea lixii dextranase were elucidated according to carbohydrate analysis by carbohydrate gel electrophoresis and high performance liquid chromatography. The molecular weigh...

Prebiotic molecules, fundamental building blocks for the origin of life, have been found in carbonaceous chondrites. The exogenous delivery these organic molecules onto Hadean Earth could sparked polymerization first RNA Darwinian ponds during wet-dry cycles. Here, we investigate formation and DNA nucleobases adenine, uracil, cytosine, guanine, thymine inside parent body planetesimals An up-to-...

The human intestine hosts a complex bacterial community that plays a major role in nutrition and in maintaining human health. A functional metagenomic approach was used to explore the prebiotic breakdown potential of human gut bacteria, including non-cultivated ones. Two metagenomic libraries, constructed from ileum mucosa and fecal microbiota, were screened for hydrolytic activities on the pre...

As of today, the most credible scientific paradigm pertaining to the origin of life on Earth is undoubtedly the RNA World scenario. It is built on the assumption that catalytically active replicators (most probably RNA-like macromolecules) may have been responsible for booting up life almost four billion years ago. The many different incarnations of nucleotide sequence (string) replicator model...

Prebiotic oligosaccharides have the ability to generate important changes in the gut microbiota composition that may confer health benefits to the host. Reducing the impurities in prebiotic mixtures could expand their applications in food industries and improve their selectivity and prebiotic effect on the potential beneficial bacteria such as bifidobacteria and lactobacilli. This study aimed t...

One of the most important open issues in astrochemistry and astrobiology is the detection in space of complex organic molecules, in particular those having a strong prebiotic role (i.e., related to the formation of biomolecule building blocks), and the identification of the chemical routes for their production. By means of selected examples, the role of rotational spectroscopy and quantum chemi...

Packaged Facts estimates the global retail market for probiotic and prebiotic foods and beverages at approximately $15.4 billion in 2008; that total represents a 12.5% increase over estimated 2007 sales of $13.7 billion. In 2008, the growth rate for the probiotic and prebiotic food and beverage market ranged from 5% to more than 30%, depending on the region and product type. Packaged Facts anal...

The search for prebiotic, nucleic acid precursors is, at its best, a speculative undertaking. Given the complex structure of RNA, it is not very likely that RNA was the first information system in the universe and thus finding possible precursor/s i.e. pre-RNA remains an open challenge. We, in this paper, have tried to construct nucleic acid polymers with a simple acyclic, achiral backbone. Suc...

BACKGROUND Galactooligosaccharides are selectively fermented by the beneficial member of the colonic microflora contributing to the health of the host. OBJECTIVE We assessed the prebiotic potential of a novel galactooligosaccharide produced through the action of beta-galactosidases, originating from a probiotic Bifidobacterium bifidum strain, against a galactooligosaccharide produced through ...