introduction: most b-cell malignancies are diagnosed based on morphologic and immunohistochemical criteria. some cases, however, still present a challenge for the pathologist to discriminate between reactive hyperplasia and neoplastic disorders. molecular techniques can be used as a helpful diagnostic tool in these cases. in this study, we assessed the value of polymerase chain reaction (pcr) t...

Diffuse Large B-Cell Lymphoma is characterized by the infiltration of small vessels lymphoid cells. These cells are not seen in systemic circulation. Depending on involvement location, it may present with different clinics such as central nervous system and skin involvement. Therefore, diagnosis delay. Diagnosis based pathology. Herein we a rare patient who initially presented cellulitis was ul...

Mantle cell lymphoma is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. The gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. Multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...

Correspondence: Ann S. LaCasce, M.D., Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA. Telephone: 617-632-5959 Fax: 617-632-5890; e-mail: [email protected] Received March 20, 2006; accepted for publication April 11, 2006. ©AlphaMed Press 1083-7159/2006/$20.00/0 Abstract Post-transplant lymphoproliferative disorder is the most common malignancy, with t...

  Background and Objective: Approximately half of patients with diffuse large B-cell lymphoma are cured with current chemotherapy regimens. The purpose of this study was to evaluate Bax and Bcl2 expression and their relationship with the response to chemotherapy. Materials and Methods This study was a prospective analysis on 44 patients with diffuse large B-cell lymphoma. Their specimens we...

Peripheral T-cell lymphomas are a group of heterogeneous disorders and according to WHO classification, are categorized into nodal and extranodal forms. NK/T-cell lymphoma, nasal type, is a subtype of extranodal peripheral T-cell lymphoma and commonly presents as a midfacial destructive lesion. This disorder is more prevalent in Asia and South America and has a strong association with Epstein B...