background drug design against human immunodeficiency virus type 1 (hiv-1) integrase through its mechanistic study is of great interest in the area in biological research. the main obstacle in this area is the absence of the full-length crystal structure for hiv-1 integrase to be used as a model. a complete structure, similar to hiv-1 of a prototype foamy virus integrase in complex with dna, in...

The Hydrologic Research Laboratory of the National Weather Service Office of Hydrology is developing its next generation of software for the conduct of the National Weather Service Hydrologic Services Program. The Integrated Hydrologic Forecast System (IHFS) project is currently focused on developing and prototyping software and data architecture components of the system. The prototype involves...

<span>Standard laboratory soil testing is deemed to be expensive and time-consuming. Utilizing a test kit considered cost-efficient time-saving way of testing. This project study aims develop prototype that detects parameters (i.e., pH, nitrogen, phosphorus, potassium) gives crop fertilizer recommendations after the sample has undergone treatment its acceptability for possible users. The ...

This paper compares the user feedback obtained from viewing a video prototype of a domestic Ambient Intelligence application called MatchMaker to that obtained by evaluating the user experience in a home simulation laboratory. The video was reverse engineered, from the final application to ensure that it provides a valid representation of the system tested in the lab. The comparison indicates t...

This article reports the development and construction of a 1:1 scale laboratory prototype of a System for Catchment, Pre-treatment and Treatment (SCPT) of runoff polluted by contaminants washed from impervious pavements. The concept of the SCPT is an online system with an up-flow filter. The filter is composed of geotextile layers and limestone. The laboratory tests carried out were focused on ...

This paper investigates the scaling of sediment transport by waves in the nearshore. Scaling of sediment is often needed in laboratory wave flumes where spatial dimensions are about a factor 10 smaller. Generally, for the physical model, normal sand is chosen with a relatively small diameter. Scaling relations are consulted to translate the spatial dimension and sediment flux to prototype value...

Unpleasant specimens, sensitive analytes, and a lengthy chromatographic procedure were the main reasons we implemented fecal porphyrin analysis with a laboratory robot. We describe the system in detail and compare it with the same technique performed manually. The day-to-day variation of assays of standards was lower with the robot than with the manual operation: 8% (CV) for coproporphyrin I an...

OBJECTIVE Renal stone formation is a multifactorial process depending in part on urine composition. Other parameters relate to structural or pathological features of the kidney. To date, routine laboratory estimation of urolithiasis risk has been based on determination of urinary composition. This process requires collection of at least two 24 h urine samples, which is tedious for patients. The...

This paper provides experimental and simulation tools to characterize a Photo-Voltaic (PV) panel. To achieve this objective, we start from a PV electrical model and we propose a circuit using Diode-based-equivalent PV (DBEPV) panel. This circuit is presented as a prototype of an equivalent PV panel. It is designed to emulate a real PV module in different climatic conditions (irradiance and temp...

A new educational power electronics laboratory based on state-of-the-art tools and industrial-grade platforms is presented in this paper. The developed laboratory, which is built based upon prior theoretical knowledge and background of the students in power electronics, combines the sophisticated Texas Instruments (TI)’s hardware tools with MATLAB/Simulink software tools to design, test, and ra...