Two distinctly different L-threonine deaminases are known to be formed in Escherichia coli. One of them participates in the biosynthesis of L-isoleucine from L-threonine and is susceptible to an end product inhibition by the former compound (1). The other one seems to participate in the catabolism of L-threonine under anaerobic conditions and is activated by adenosine 5’monophosphate (1, 2). Li...

The recent formulation (1, 2) of the structure of vitamin Brz prompts us to report an investigation conducted several years ago on the origin of its aminopropanol component. Previous studies on the metabolism of L-threonine in rats had shown that it was cleaved mainly to acetate and glycine (3,4). The decarboxylation of threonine to the corresponding amine could not be demonstrated, within the ...

The gene encoding threonine synthetase has been located by genetic transformation in Bacillus subtilis. Its position is adjacent and central to the genes encoding homoserine dehydrogenase and homoserine kinase. Its mutational sites are closely linked to, and interspersed among, several mutational sites affecting a minor but phenotypically significant threonine dehydratase (distinct from the maj...

BACKGROUND The threonine requirement of human neonates who receive parenteral nutrition (PN) has not been determined experimentally. OBJECTIVE The objective was to determine the parenteral threonine requirement for human neonates by using the minimally invasive indicator amino acid oxidation technique with L-[1-(13)C]phenylalanine as the indicator amino acid. DESIGN Nine postsurgical neonat...

Cadmium is a highly toxic metal that can damage a number of organs including the gastrointestinal tract. It has been shown that cadmium partially reduces L-threonine intestinal absorption probably by binding to membrane proteins which pertain to active transport systems or are functionally related to them. Calcium, however, is an essential element in a wide variety of cellular activities. The a...

An experiment was conducted to evaluate the effect of form and particle size of feed supplemented with L- threonine on growth performance, carcass characteristic and blood biochemical parameters of broiler chickens. The experimental design was a 2 × 2 × 2 factorial arrangement of treatments evaluating two feed forms (pellet or mash), two feed particle sizes (fine or course), and two inclusion r...

BACKGROUND L-Threonine is an important amino acid for animal feed. Though the industrial fermentation technology of threonine achieved a very high level, there is still significant room to further improve the industrial strains. The biosensor-based high-throughput screening (HTS) technology has demonstrated its powerful applications. Unfortunately, for most of valuable fine chemicals such as th...

L-Threonine has been widely used as a supplement in the food, pharmaceutical, and cosmetic industries. Here, we present a high-quality draft annotated genome sequence of Escherichia coli XH001, a producer of L-threonine in industry. Its genome and plasmid sequence will provide clues about the molecular mechanisms underlying its beneficial properties.

Reinvestigation of the growth of L-proline succinate (1) (Paramasivam and Ramachandra Raja, Journal of Crystallization Process and Technology, 2 (2012) 21 24; Balamurugaraj et al., Journal of Material Physics and Chemistry 1 (2013) 4 8) and L-threonine zinc acetate (2) (Puhal Raj and Ramachandra Raja, Photonics and Optoelectronics, 2 (2013) 56 64) is reported. Slow evaporation of an aqueous sol...

The observation that Leuconostoc dextranicum 8086 requires either aspartic acid or threonine for growth resulted in studies in which a ri%e’ of aspartic acid in the biosynthesis of threonine was demonstrated in certain lactobacilli (1). In the present investigation, the nature of the requirement for either aspartic acid or threonine for growth of L. dextranicum 8086 has been found to be the res...