abstract we report a case of paint thinner intoxication by inhalation, with rhabdomyolysis, renal failure, skin lesions and severe sciatic nerve lesion at gluteal region.

Traumatic brain injury (TBI) is a heterogeneous syndrome that includes various types of trauma. About 10–15 % patients have severe TBI, accompanied by high rates disability and mortality. Currently, the methods intensive care from standpoint evidence-based medicine are widely used for their treatment. Along with care, comprehensive cytoprotective program using Neurocitin®, which contains citico...

RATIONALE Acute alcohol intoxication selectively impairs executive functioning and prospective memory (PM). Much previous researches in this area have used laboratory‐based tasks that may not mimic functions that individuals with dysexecutive syndrome have problems with in their everyday life. The present study aimed to assess the effects of a modest dose of alcohol on executive functioning and...

Gamma-hydroxybutyric acid (GHB) is gaining popularity as a drug of abuse. Reports of toxicity and lethality associated with GHB use have increased. This survey study was designed to identify patterns of GHB use, its effects, and withdrawal syndrome. A survey inquiring about the effects of GHB was administered to 42 users. The results showed that GHB was used to increased feelings of euphoria, r...

Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor beans), is one of the most lethal toxins known, particularly if inhaled. Ricin is considered a potential biological threat agent due to its high availability and ease of production. The clinical manifestation of pulmonary ricin intoxication in animal models is closely related to acute respiratory distress syndro...

We report the case of a collective intoxication by ingestion of a mushroom "Lepiota brunneoincarnata" at the origin of the death of four members of the same family aged between 3 and 15 year old. We discuss the physiopathology and the prognosis factors of such intoxications through these four observations which highlight the clinical signs, biological disturbances due to the intoxication, autop...

We report the case of a collective intoxication by ingestion of a mushroom “Lepiota brunneoincarnata” at the origin of the death of four members of the same family aged between 3 and 15 year old. We discuss the physiopathology and the prognosis factors of such intoxications through these four observations which highlight the clinical signs, biological disturbances due to the intoxication, autop...

In guinea-pigs, the oral and subcutaneous LD50 values were very similar (cf. 0,173 mg/kg over 48 h with 0,116 mg/kg over 24 and 48 h). When dosed subcutaneously, a cumulative effect was observed. Intravenous administration of cotyledoside to anaesthetized guinea-pigs resulted in: dyspnoea, increased heart rates and blood pressures, and electrocardiagraphic changes typical of cardiac glycoside p...

Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor beans), is one of the most lethal toxins known, particularly if inhaled. Ricin is considered a potential biological threat agent due to its high availability and ease of production. The clinical manifestation of pulmonary ricin intoxication in animal models is closely related to acute respiratory distress syndro...