Multileaf collimators (MLCs) are the prevailing tool for the realization of radiation fields in intensity modulated radiation therapy (IMRT). One step in the treatment planning is to determine a set of leaf positions realizing a certain intensity modulated radiation field. In this paper we suggest two extensions in the use of the MLC that lead to considerable savings in terms of monitor units, ...

Homogeneous target dose distribution in intensity-modulated radiotherapy (IMRT) for sinonasal cancer (SNC) is challenging to achieve. To solve this problem, we established and evaluated a basal-dose-compensation (BDC) optimization approach, in which the treatment plan is further optimized based on the initial plans. Generally acceptable initial IMRT plans for thirteen patients were created and ...

Intensity modulated radiation therapy (IMRT) and three-dimensional conformal radiation therapy (3D CRT) are two treatment modalities in prostate cancer, which provide acceptable dose distribution in tumor region with sparing the surrounding normal tissues. IMRT is based on inverse planning optimization; in which, intensity of beams is modified by using multileaf collimators and also compensator...

A Sensitivity-Driven Greedy Approach to Fluence Map Optimization in Intensity-Modulated Radiation Therapy