نتایج جستجو برای: hypothyroid
تعداد نتایج: 2540 فیلتر نتایج به سال:
Rats rendered hypothyroid by treatment with methimazole develop an exaggerated sodium appetite. We investigated here the capacity of hypothyroid rats (N = 12 for each group) to respond to a low dose of captopril added to the ration, a paradigm which induces an increase in angiotensin II synthesis in cerebral areas that regulate sodium appetite by increasing the availability of circulating angio...
OBJECTIVE Rheumatoid arthritis (RA) patients have an increased risk of developing cardiovascular diseases (CVD). Other autoimmune diseases such as hypothyroidism are also associated with an enhanced risk for CVD. Our objective was to determine first, the prevalence of hypothyroid disorders in RA patients, and second, the risk of CVD in RA patients with hypothyroid abnormalities. METHODS SU...
The ability of catecholamines and glucagon to stimulate glycogen phosphorylase activity was examined in hepatocytes isolated from euthyroid and hypothyroid fed female rats. Hypothyroidism did not alter the ability of either phenylephrine or epinephrine to activate glycogen phosphorylase. Activation of glycogen phosphorylase in response to a maximal concentration of isoproterenol, however, was 1...
We have studied the regulation of rat intestinal and hepatic apolipoprotein gene expression, in vivo, after alterations in thyroid hormone status. When compared to those of chow-fed controls, rates of synthesis of intestinal apoA-I and apoB-48 decreased 60-66% in hypothyroid animals and increased three- to fourfold after triiodothyronine (T3) administration. These changes were not accompanied b...
BACKGROUND Adult hypothyroidism is a highly prevalent condition that impairs processes, such as learning and memory. Even though tetra-iodothyronine (T(4)) treatment can overcome the hypothyroidism in the majority of cases, it cannot fully recover the patient's learning capacity and memory. In this work, we analyzed the cellular and molecular changes in the adult brain occurring with the develo...
In hypothyroid patients, altered microvascular structure and function may affect mood and cognitive function. We hypothesized that adult male hypothyroid rats will have significantly lower forebrain blood vessel densities (BVD) than euthyroid rats and that treatment with 3,5-diiothyroprionic acid (DITPA) (a thyroid hormone analog) or thyroxine (T(4)) will normalize BVDs. The euthyroid group rec...
Background: Up until now, the effect of thyroid hormones on the male reproductive organ, after puberty, is not well understood. OBJECTIVES: In the present study, the morpho-histometrical effects of thyroid hormone deficiency on the adult-male rat reproductive organs were investigated. MATHODS: Thirty adult male rats were randomly divided into three groups (n=10): control, hypothyroid, and hypot...
Introduction: Hypothyroidism is a disease that reduces production of thyroid hormones (T4 &­T3) and it is one of the potential causes of mental disorders. In addition to somatic signs and symptoms, some other problems such as depression, anxiety, stress, psychomotor delayed and cognitive disorder are seen in hypothyroidism. The purpose of this study is to compare anxiety and stress in...
This research was conducted to determine the effect of Coenzyme Q10 (CoQ10) on blood glucose, total protein, triglyceride, and cholesterol levels in rats for that experimental hypothyroidism induced. A 32 healthy adult male Wistar Albino were used as a material research. After adaptation period animals ten days, main three weeks. The housed four each cage during divided into groups control (K),...
ion fluxes in these cells, we have now examined the possibility that the decrease in beta receptor number might be associated with concomitant changes in catecholamine-dependent potassium ion transport. Hypothyroid turkey erythrocytes display decreased sensitivity to isoproterenol-stimulated potassium influx. Half-maximal stimulation of potassium influx occurs at 9.2±+1.7 nM in hypothyroid cell...
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