periodic paralysis is a rare disorder characterized by transient attacks of flac-cid paralysis of varying intensity and frequency. Although mostly familial in etiology, several sporadic cases with different causes have been reported, including some resulting from renal tubular acidosis. 1 This article reports the case of a young man with secondary hypokalemic periodic paralysis caused by distal...

PURPOSE Presenting the case of unusual onset hypokalemic periodic paralysis (HypoPP) where myopathy had developed two years before paralysis occurred. MATERIAL AND METHODS A Polish three-generation family with HypoPP and mutation in CACNA1S (R1239G) has been investigated. Clinical presentation with unusual onset of the disease, biopsy results and genetic research in one family member were des...

A 17-year-old girl suffered from episodes of flaccid paralysis during each menstrual cycle. No relevant changes were found in potassium concentrations in serum or erythrocytes, nor in the values of pituitary, ovarian, adrenal or thyroid hormones. Acetazolamide administration prevented the attacks.

Neurology S. L. Venance, K. Jurkat-Rott, F. Lehmann-Horn and R. Tawil SCN4A-associated hypokalemic periodic paralysis merits a trial of acetazolamide This information is current as of November 24, 2007 http://www.neurology.org/cgi/content/full/63/10/1977 located on the World Wide Web at: The online version of this article, along with updated information and services, is All rights reserved. Pri...

hypokalemic disease is a disorder in which the amount of serum’ s potassium declines and the patient faces limbs weakness. in this disease, eye muscle and respiratory muscles rarely become involved and death may follow due to respiratory paralysis and heart conducting disturbances. since this disease is treatable and progressive weakness can be prevented, therefore in the study conducted we att...

BACKGROUND periodic paralysis related to hypokalemia is seldom reported in thyrotoxicosis, and it usually occurs in Asian males. PATIENTS AND METHODS Two Romanian (Caucasian) young patients presented with hypokalemic paralysis. TSH, FT4, TT3 was measured by immunochemiluminescence. Case report 1. Patient O.R, aged 19, presented marked asthenia and lower limbs paralysis, following high carbohy...

OBJECTIVES To identify a clinically reliable index of thyrotoxic periodic paralysis (TPP), a life-threatening emergency with unique and effective therapies. DESIGN Diagnostic study. SETTING University teaching hospital. PATIENTS Fifty-three consecutive patients with hypokalemic paralysis during a 3-yr period and 30 thyrotoxic patients without paralysis as the thyrotoxic control group. I...

A 19-year-old white man with familial hypokalemic periodic paralysis developed evidence of cardiac dysfunction during a episode of flaccid paralysis. This consisted of elevated total creatine phosphokinase (CPK), an increased myocardial fraction of CPK (myocardial band), alteration in the lactic dehydrogenase isoenzyme pattern, severe bradycardia, and evidence of left ventricular dysfunction. T...