نتایج جستجو برای: hsv
تعداد نتایج: 8738 فیلتر نتایج به سال:
Rapid confirmation of herpes simplex virus (HSV) is essential in many clinical settings. Viral isolation in cell culture is the standard method for diagnosing HSV infection, with confirmation by specific immunological staining. The performance of the Rapid Absorbent Matrix Pad (RAMP) HSV culture confirmation test was evaluated with specimens obtained from 71 patients with suspected HSV infectio...
Background: It was shown that olive leave extract has antifungal, antibacterial and antiviral activities. The effects of OLE on herpes simplex virus-1 (HSV-1) have not been systematically investigated yet. The aim of this study was to examine the in vitro effect of olive leaf hydroalcoholic extract (OLHE) on HSV-1. Methods: Virucidal effect and viral replication in Vero cell line were studied i...
During lytic herpes simplex virus (HSV) infections, the HSV virion host shutoff protein (UL41) accelerates the turnover of host and viral mRNAs. Although the UL41 polypeptides from HSV type 1 (HSV-1) strain KOS and HSV-2 strain 333 are 87% identical, HSV-2 strains generally shut off the host more rapidly and completely than HSV-1 strains. In a previous study, we identified three regions of the ...
CONTEXT Herpes simplex virus type 1 (HSV-1) and type 2 are common infections worldwide. Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes and is almost always sexually transmitted. In contrast, HSV-1 is usually transmitted during childhood via nonsexual contacts. Preexisting HSV-1 antibodies can alleviate clinical manifestations of subsequently acquired HSV-2. Furthermore,...
Background and Objective: Herpes Simplex Type 2 (HSV-2) causes vaginal and cervical infections in women. The diagnosis of this virus is not a routine test in medical laboratories and therefore in many cases this infection is not diagnosed and reported. Consequently, the majority of women have a little information about this infection. The aim of this study was to determine the frequency of HSV-...
Abstract Background and objectives: Herpes simplex virus type two (HSV-2) infections are mostly considered as a sexually transmitted disease. It causes genital herpes, newborn herpes non-pyrogenic meningitis and may act as an underlying factor for HIV infection. This study was conducted to determine the sero-epidemiologic prevalence of herpes simplex virus type two in cases referred to ten clin...
Background: Cumin (Cuminum cyminum L. [family Apiaceae]) seed essential oil is reported to have antiseptic activity. Until now the antiviral properties of cumin seed extracts on viruses such as herpes simplex virus-1 (HSV-1) have not been studied. The objective of this study was to investigate the in vitro effects of aqueous, methanolic and hydroalcoholic extracts of cumin seed on HSV-1 growth ...
Herpes Simplex Virus (HSV) is a double-stranded DNA virus in the Herpesviridae family. The most prevalent humans Human Type 1 (HSV-1). It can reach brain without causing symptoms [1]. Currently, antiviral drug used Acyclovir (ACV); nucleotide analogues target polymerase inhibiting viral replication. However, ACV drug-resistant occurs, especially immunocompromised patients [2]. Therefore, altern...
Background: An andrographolide analogue, 3,19-isopropylideneandrographolide (IPAD), exert an inhibitory effect on herpes simplex virus serotype 1 (HSV-1) wild types replication. In this study, we examined the anti-viral activity of IPAD on HSV-1 and HSV-2 wild types and HSV-1 drug-resistant strains (DRs). Synergistic effects of IPAD with ACV were also evaluated. Methods: MTT and plaque reductio...
The entry of herpes simplex virus (HSV) into cells requires the interaction of viral glycoprotein D (gD) with a cellular gD receptor to trigger the fusion of viral and cellular membranes. Nectin-1, a member of the immunoglobulin superfamily, can serve as a gD receptor for HSV types 1 and 2 (HSV-1 and HSV-2, respectively) as well as for the animal herpesviruses porcine pseudorabies virus (PRV) a...
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