The study by Huang et al1 sheds valuable light on how obesity may cause depression. However, depressed people are known to be at higher risk for developing obesity in the first place.2 It is therefore important to know whether any of the participants had a history of prior depression. Other significant risk factors for depression such as concomitant physical illness, medication use, lack of fam...

Obesity and diabetes mellitus are two modern epidemics. But their interrelationship is debated. Here we explored the probable association among obesity, leptin and insulin resistance in type 2 diabetes mellitus. 60 recent onset (< 5 years) diabetics and age-sex matched 33 non diabetic controls were assessed for physical and chemical parameters like Body Mass Index, abdominal circumference, wais...

25 26 Erection depends largely on the release of nitric oxide (NO) by vascular endothelial cells. 27 Insulin resistance (IR) is a metabolic abnormality that produces endothelial dysfunction 28 characterized by decreased synthesis and release of NO. Aim: To evaluate the effect of 29 treatment with metformin on the response to sildenafil in patients with erectile dysfunction 30 (ED) and IR. Metho...

BACKGROUND Weight loss and increased physical fitness are established approaches to reduce cardiovascular risk factors. We studied the reduction in BMI z-score associated with improvement in cardiometabolic risk factors in overweight and obese children and adolescents treated with a combined hospital/public health nurse model. We also examined how aerobic fitness influenced the results. METHO...

Results: The real price (inflated to 2006 US dollars) of soda and pizza decreased over time; the price of whole milk increased. A 10% increase in the price of soda or pizza was associated with a −7.12% (95% confidence interval [CI], −63.50 to −10.71) or −11.5% (95% CI, −17.50 to −5.50) change in energy from these foods, respectively. A $1.00 increase in soda price was also associated with lower...

OBJECTIVE Prevalence of non-alcoholic fatty liver disease (NAFLD) among children is increasing dramatically. It is unclear why some patients develop steatohepatitis (NASH), fibrosis and cirrhosis from steatosis, and others do not. A role for leptin has been claimed. This study aims to evaluate the relationship between leptin, insulin resistance (IR) and NAFLD in children. DESIGN AND METHODS I...

Type 3 diabetes (T3D) accurately reflects that dementia, e.g., Alzheimer’s disease, represents insulin resistance and neurodegeneration in the brain. Similar retinal microvascular changes were observed chronic stressed individuals. Hence, we aimed to show stress relates T3D dementia signs retinopathy, ultimately comprising a Stress syndrome prototype reflecting risk for stroke. A stroke phenoty...

Objective: To find the correlation of the clinical and biochemical parameters in Indian adult women with PCOS with and without AN. Materials and Methods: 98 adult women (20-35years) with PCOS as per Rotterdam 2003 criteria were studied. Clinical parameters recorded Body mass index (BMI), abdominal circumference (AC), blood pressure (BP), hirsutism score (modified FerrimanGallwey score m FG ≥ 6)...

conclusions it seems that hp eradication per se might not affect lfc, lft, lipid profile, and insulin resistance in dyspeptic nafld patients. results one hundred (49 males) patients with the mean age of 43.46 (± 11.52) were studied. repeated measure anova showed a significant reduction in lfc, anthropometric measurements, and laboratory parameters (except for hdl) in the both groups during the ...