Sea-blue histiocytosis is a rare disorder seen in patients with lipid metabolic or ceroid storage diseases. Sea-blue histiocytes are ceroid-laden macrophages detectable by May-Giemsa staining. We report a case of a 28-year-old woman diagnosed with Niemann-Pick disease at 2 or 3 years of age. To confirm this diagnosis, we examined her bone marrow, which revealed scattered foci containing aggrega...

Indeterminate cell histiocytosis is a very rare proliferative disorderof histiocytes which displays both langerhans cell histiocytosisand non langerhans cell histiocytosis immunophenotypic features.The majority of the patients develop multiple lesions which areclinically indistinguishable from generalized eruptive histiocytosis.We report a 14-year-old girl with multiple papules on the face,scal...

Intralymphatic histiocytosis is a rare condition characterized by the presence of dilated lymphatic vessels containing aggregates of mononuclear histiocytes (macrophages) within their lumina. The phenomenon seems to occur almost exclusively within the reticular dermis. Although its pathogenesis remains uncertain, there has been speculation about the possible relationship between intralymphatic ...

Histiocytes and dendritic cells belong to a group of immunoregulatory cells that are responsible for antigen processing and presentation to lymphocytes. Neoplasms of histiocytic and dendritic origin are very rare [1], making up less than 1% of tumours in lymph nodes. Thus, information regarding epidemiology, prognosis and treatment [2, 3] is scarce. Table 1 summatizes the neoplasms derived from...

Abstract Background There have been many studies on the clinical characteristics of neutrophilic, lymphocytic, and/or eosinophilic pleural effusion. While caring for patients with effusion, we found that histiocytic effusion (HisPE) was not uncommon. However, few explored HisPE. The purpose present study to determine and etiologies Methods In this retrospective study, HisPE defined as fluid whi...

The pathogenesis of inflammatory bowel diseases has not been fully studied, and the therapies used have side effects that limit their use. purpose this study is to conduct a clinical immunological analysis effectiveness vitamin D 3 in original rectal suppositories experimental colitis (EC). EC was modeled with oxazolone. Original group 5-ASA 4 were per rectum . clinic evaluated on Disease activ...