نتایج جستجو برای: hepatotoxic effect
تعداد نتایج: 1642793 فیلتر نتایج به سال:
Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium genera. It hepatotoxic, nephrotoxic carcinogenic. The growing contamination of OTA in wine grape juice great threat to human. In this study, different enzymes were screened for the detoxification juice. results indicated that seven had degradation capacity buffer, rate carboxypeptidase (CPA), lipase, pancreatin thermolysi...
Herein we describe the synthesis and in vitro biological evaluation of thirteen new, racemic, diversely functionalized imidazo pyranotacrines as non-hepatotoxic, multipotent tacrine analogues. Among these compounds, 1-(5-amino-2-methyl-4-(1-methyl-1H-imidazol-2-yl)-6,7,8,9-tetrahydro-4H-pyrano[2,3-b]quinolin-3-yl)ethan-1-one (4) is non-hepatotoxic (cell viability assay on HepG2 cells), a select...
Liver being vulnerable to exogenous substances makes disease associated with it a matter of worldwide concern. Several research thus focus on hepatoprotection .Preventive and therapeutic activity plants as hepatoprotective agent is topic interest for researchers. Hepatotoxic agents like carbon tetrachloride, paracetamol, isoniazide etc. increase the serum biomarkers liver where ALT more specifi...
Paraphenylenediamine (PPD) is a chemical product used in hair dye preparations and temporary tattoos to fasten the dyeing process intensify its results. PPD can evoke local and/or systemic toxic effects either when utilized topically, inhaled or ingested. The aim of this study was evaluate on liver adult female albino rats. Thirty-two rats were divided into 3 groups. Group I (control group) 16 ...
Carbon tetrachloride (CC14) is considered as one of the environmental pollutants which mainly caused hepatotoxic effect; it is most widely used for experimental induction of hepatic cirrhosis [1] CCl4 induces liver necrosis, fibrosis, cirrhosis and acute tubular necrosis in the kidney [2] In addition, CCl4 also alters the antioxidant profile of the liver including the antioxidant enzymes like s...
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