BACKGROUND Heart Failure (HF) is a common disease with a high mortality rate. Anaemia and renal failure (RF) are often present in patients with HF and associated with worse prognosis. Objective of study was to evaluate the prevalence of anaemia and RF in patients with HF. METHODS Patients admitted in Punjab institute of cardiology Lahore with diagnosis of heart failure were enrolled from Febr...

Hospital admissions with heart failure (HF) are increasing worldwide. It is the main reason for hospitalization of elderly patients. Heart failure affects nearly 15% of patients aged >75 years. Prognosis after diagnosis of HF is comparable to that of cancers with 50% survival after 4 years of mild HF and 50% after one year in more severe cases. Current data increasingly suggest that measurement...

Heart failure (HF) is a syndrome characterized by high mortality, frequent hospitalization, reduced quality of life, and a complex therapeutic regimen. Knowledge about HF is accumulating so rapidly that individual clinicians may be unable to readily and adequately synthesize new information into effective strategies of care for patients with this syndrome. Trial data, though valuable, often do ...

Heart failure (HF) is a syndrome characterized by high mortality, frequent hospitalization, reduced quality of life, and a complex therapeutic regimen. Knowledge about HF is accumulating so rapidly that individual clinicians may be unable to readily and adequately synthesize new information into effective strategies of care for patients with this syndrome. Trial data, though valuable, often do ...

BACKGROUND Growing evidence exists for soluble Angiotensin Converting Enzyme-2 (sACE2) as a biomarker in definitive heart failure (HF), but there is little information about changes in sACE2 activity in hypertension with imminent heart failure and in reverse remodeling. METHODS, FINDINGS Patients with systolic HF (NYHAII-IV, enrolled for cardiac resynchronisation therapy, CRT, n = 100) were c...

T he proliferation of costly therapies has led to an increased focus on value. In the treatment of patients with advanced heart failure (HF), one such expensive intervention, CardioMEMS (CardioMEMS Heart Failure System, St. Jude Medical Inc., Atlanta, Georgia), is a permanently implanted device to monitor pulmonary artery pressure and enable adjustments in therapy that could avert the need for ...

A early reports of erythropoiesis-stimulating agents (ESAs) having success correcting anemia in heart failure (HF), the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) study, a large phase III trial, demonstrated that darbepoetin alfa was not able to improve clinical outcomes in patients with HF who had reduced ejection fraction and mild to moderate anemia, and indeed, it led ...

BACKGROUND Chronic heart failure (HF) is characterized by diminished cardiac output and pooling of blood in the venous system. AIM We used the GSE1145 microarray data to identify potential genes that related to heart failure to construct a regulation network. MATERIALS AND METHODS In the network, some of transcription factors (TFs) and target genes have been proved to be related to heart fa...

.. Objectives: To determine the frequency of new onset heart failure after acute myocardial infarction and factors contributing it. Methods: A total of 228 patients were studied for occurrence of new onset clinical heart failure within24 hours after admission with an acute Myocardial Infarction. Clinical parameters were used to diagnose heart failure. Various risk factors were analyzed which co...

BACKGROUND The characteristics and outcomes of patients discharged from hospitals with a diagnosis of heart failure (HF) have been described by a number of previous epidemiological studies. However, very little information is available on this issue in general practice in Japan. METHODS AND RESULTS The Japanese Cardiac Registry of Heart Failure in General Practice (JCARE-GENERAL) is designed ...