Highlights from the first European Conference on Computational Biology (ECCB 2002), held in conjunction with the German Conference on Bioinformatics (GCB 2002), 6-9 October 2002, Saarbrücken, Germany.

This paper compares the performance of diode clamped three level inverter based STATCOM with sinusoidal and space vector PWM techniques. Space Vector Pulse Width Modulation (SVPWM) technique is the most advantageous technique than the conventional sinusoidal PWM technique for a multilevel inverter. The space vector pulse width modulation technique is an advanced, computation-intensive PWM metho...

A full-order dynamic model of the pulse-width modulation (PWM) DC-to-DC SEPIC converter in discontinuous conduction mode (DCM) is presented in this paper. The derivation procedure is based on the smallsignal PWM switch model in DCM used in conjunction with a PWM derived SEPIC topology. The small-signal characteristics of the PWM SEPIC converter in DCM obtained in a similar way as the small-sign...

In this paper, we propose a PWM (Personal Web Map) which is a personal and small database of interesting Web pages to a user, and develop a method to construct it under the user’s control of multiple Web robots. Though general search engine with large databases like YaHoo, AltaVista, MetaCrawler are valid, it is important that a user constructs a small, personal database of relevant Web pages t...

Position weight matrix (PWM) is not only one of the most widely used bioinformatic methods, but also a key component in more advanced computational algorithms (e.g., Gibbs sampler) for characterizing and discovering motifs in nucleotide or amino acid sequences. However, few generally applicable statistical tests are available for evaluating the significance of site patterns, PWM, and PWM scores...

Partial monitoring games are repeated games where the learner receives feedback that might be different from adversary’s move or even the reward gained by the learner. Recently, a general model of combinatorial partial monitoring (CPM) games was proposed [1], where the learner’s action space can be exponentially large and adversary samples its moves from a bounded, continuous space, according t...

CONTEXT AND OBJECTIVE Gene expression and immunohistochemical profiling of diffuse large B-cell lymphoma (DLBCL) have revealed important prognostic subgroups: germinal center B-cell-like (GCB-like) DLBCL and activated B cell-like (ABC-like) DLBCL. Although few reports on high-risk DLBCL are available, the prognosis for the GCB-like subgroup has been shown to be better than that of the ABC-like ...

Classification of diffuse large B-cell lymphoma (DLBCL) into cell-of-origin (COO) subtypes based on gene expression profiles has well-established prognostic value. These subtypes, termed germinal center B cell (GCB) and activated B cell (ABC) also have different genetic alterations and overexpression of different pathways that may serve as therapeutic targets. Thus, accurate classification is e...

Classification of diffuse large B-cell lymphoma (DLBCL) into cell-of-origin (COO) subtypes based on gene expression profiles has well-established prognostic value. These subtypes, termed germinal center B cell (GCB) and activated B cell (ABC) also have different genetic alterations and overexpression of different pathways that may serve as therapeutic targets. Thus, accurate classification is e...