Secondary hyperparathyroidism in pseudohypoparathyroidism was suggested by Kolb (1962) based mainly on bone X-ray findings characteristic to parathyroid hyperfunction such as subperiosteal resorption and osteitis fibrosa. We have recently experienced a case of typical pseudohypoparathyroidism in which the parathyroid hormone-like calcium-mobilizing activity in urine was increased, although bone...

While the mechanical behaviors of the fibrosa and ventricularis layers of the aortic valve (AV) leaflet are understood, little information exists on their mechanical interactions mediated by the GAG-rich central spongiosa layer. Parametric simulations of the interlayer interactions of the AV leaflets in flexure utilized a tri-layered finite element (FE) model of circumferentially oriented tissu...

A NUMBER of bone diseases may affect the orbital bones decreasing the orbital volume and narrowing the optic canal, giving rise to unilateral exophthalmos and usually optic atrophy, simulating clinically an orbital tumour. Among such diseases are osteitis deformans (Paget, 1876); leontiasis ossea (Virchow, 1896); osteopetrosis (Albers-Schonberg, 1904), and the generalized and localized osteitis...

Although bone disease and stone disease are the universally accepted classical manifestations of primary hyperparathyroidism, clinical parathyroid bone disease is rarely seen today in the United States (<5% of patients) and Western Europe. Nevertheless, in a given patient, classical skeletal involvement can be the first sign of primary hyperparathyroidism, but not recognized because it is not u...

'Brown tumors' are known as 'osteitis fibrosa cystica' or 'Von Recklinghausen's disease' of the bone. A high index of suspicion is required by the treating doctor for diagnosing a 'brown tumor' in its early stage. Clinical suspicion, along with laboratory and radiological investigations, is required to diagnose this condition. We present a case of a 65-year-old woman who had multiple bony lesio...

A 65-year-old man with back pain had plain radiographs that showed multiple osteolytic bone lesions of the pelvis, femur and L-spine; an magnetic resonance imaging scan of the L-spine showed extensive bony resorption with a posterior epidural mass involving the L1 spinous process; these findings suggested multiple myeloma or bony metastasis. However, all serology testing was negative. The parat...

or disseminated sclerosis but I was told that she had had some pain around the groin, that her doctor had sent her for X-ray of the pelvis, and that a large destructive lesion had been found in one of the pubic rami. A surgeon saw her and advised that she should be admitted to a chronic hospital: the diagnosis was secondary tumours of bone. When I first looked at this X-ray picture of the pubis...

The authors compared porcine corneal and scleral membrane phospholipids determined with use of 31P nuclear magnetic resonance (NMR). These tissues make up the tunica fibrosa (outer coat) of the eye. Since the sclera, unlike the cornea, does not possess an epithelium or an endothelium, comparative analysis of these tissues included examination of the cornea with and without its epithelium and en...