This study compared the two following hydrodensitometric methods for estimating percent body fat (%BF): 1) estimation of residual volume (RV) by helium dilution before and after measurement of immersed mass at RV, and 2) determination of immersed mass at a comfortable level of expiration (approximately functional residual capacity) with measurement of the associated gas volume by oxygen dilutio...

Nitrogen multiple-breath washout (N2MBW) is increasingly used in patients with cystic fibrosis. The current European Respiratory Society/American Thoracic Society consensus statement for MBW recommends the rejection of measurements with leaks. However, it is unclear whether this is necessary for all types of leaks. Here, our aim was to 1) model and 2) apply air leaks, and 3) to assess their inf...

BACKGROUND Rosacea is a common, incurable skin barrier disorder characterized by relapses and remissions. PURPOSE To evaluate the efficacy of Farmaka Rosacea Cream (FRC), a novel topical formulation for rosacea. METHODS This single-center, open-label pilot study comprised a single-dose substudy in 20 healthy subjects and a long-term, repeat-dose substudy in 22 subjects with rosacea. The 2-h...

BACKGROUND End tidal inspiratory activity (ETIA) in diaphragm and parasternal intercostal muscles can be evoked in man and in animals by administration of histamine. Exacerbations of asthma and administration of histamine are often accompanied by hyperinflation. The aims of the study were to determine (1) the magnitude of ETIA in response to histamine in man, (2) the relative contributions of c...

During dynamic hyperinflation with induced bronchoconstriction, there is a reduction in lung elastic recoil at constant lung volume (R. Pellegrino, O. Wilson, G. Jenouri, and J. R. Rodarte. J. Appl. Physiol. 81: 964-975, 1996). In the present study, lung elastic recoil at control end inspiration was measured in normal subjects in a volume displacement plethysmograph before and after voluntary i...

The aim of the study was to determine the static load-bearing capacity of fractured incisal teeth restored with the conventional adhesive-composite technique or by using fiber reinforced composites (FRC). Upper incisal teeth were prepared by cutting the incisal part of the crown horizontally. Restorations were made by three techniques. Group A (control group) was restored by reattaching the ori...

There is no clear evidence as to how maximal inspiratory mouth pressure (PI,max) should be measured, although plateau pressures sustained for 1 s and measured at residual volume (RV) are usually recommended. Peak and plateau PI,max were measured at RV and at functional residual capacity (FRC) in 533 healthy subjects (aged 10-90 yrs) in order to comparably test all PI,max measurements for their ...

Nitrogen excreted from body tissues impacts the calculation of multiple breath nitrogen washout (MBWN2) outcomes. The aim of this study was to determine the effect of tissue N2 on MBWN2 outcomes in both healthy subjects and patients with CF and to assess whether it is possible to correct for tissue N2. The contribution of tissue N2 to MBWN2 outcomes was estimated by comparing MBWN2-derived func...

treatable with standard mycobacterial chemotherapy), and groups 2a and 2b (difficult to treat with usual mycobacterial therapy). Functionally, this seems to be a practical way for clinicians who do not frequently encounter these many microbes to keep track of the clinical importance of isolates. However, I am concerned about the predictable overlap of the old classification system of Runyon wit...

treatable with standard mycobacterial chemotherapy), and groups 2a and 2b (difficult to treat with usual mycobacterial therapy). Functionally, this seems to be a practical way for clinicians who do not frequently encounter these many microbes to keep track of the clinical importance of isolates. However, I am concerned about the predictable overlap of the old classification system of Runyon wit...