We study the effects of non-commutative QED (NCQED) in fermion pair production, γ + γ → f + f̄ and Compton scattering, e + γ → e + γ. Non-commutative geometries give rise to 3and 4-point photon vertices and to momentum dependent phase factors in QED vertices which will have observable effects in high energy collisions. We consider ee colliders with energies appropriate to the TeV Linear Collider...

With the completion of the Lep-2 operation, the exploration of the high energy frontier in e + e − physics is most likely to be inherited by a linear collider (LC). In fact, the E 4 beam scaling of the beam energy loss in circular storage rings makes them no longer a viable choice for collision energies beyond about 300 GeV. A rich harvest of physics results should become accessible at centre-o...

Using Tunable Nanoscale Confinement to Image and Manipulate DNA Daniel Berard, Jason S. Leith, Francois Michaud, Sabrina R. Leslie Department of Physics, McGill University, Canada [email protected] We present a modular microscopy device that transforms a basic inverted fluorescence microscope into a versatile single-molecule imaging and diagnostic system, with applications in the biome...

CLIC is one of the current projects of high energy linear colliders. Vertical beam sizes of 1nm at the collision point and fast ground motion of a few nanometres impose an active stabilization of the final doublets at a tenth of a nanometre above 5Hz. The majority of our work concerned vibrations and active stabilization studies of cantilever and slim beams in order to be representative of the ...

The CLIC test facility 3 (CTF3) provides a 3.5A, 1.6μs electron beam pulse of 150MeV at the end of the linac. The average beam power is 4 kW. Beam losses will be monitored all along the linac in order to keep the radiation level as low as possible. The heavy beam loading of the linac can lead to time transients of beam position, size and energy along the pulse. To compensate for these transient...

Fluorescence imaging is used to study the dynamics of a wide variety of single molecules in solution or attached to a surface. Two key challenges in this pursuit are (1) to image immobilized single molecules in the presence of a high level of fluorescent background and (2) to image freely diffusing single molecules for long times. Strategies that perform well by one measure often perform poorly...

The objectives of the CLIC Test Facility (CTF) are to study the generation of short intense electron bunches using a laser driven photocathode in an RF gun, to generate 30 GHz RF power for high gradient tests of prototype CLIC components, and to test beam position monitors. The performance of the CTF has improved dramatically in the course of the past year and highlights are presented here. The...

The chloride intracellular channel (CLIC) family of proteins has the remarkable property of maintaining both a soluble form and an integral membrane form acting as an ion channel. The soluble form is structurally related to the glutathione-S-transferase family, and CLIC can covalently bind glutathione via an active site cysteine. We report approximately 0.6 μs of molecular dynamics simulations,...

Here we present a high-throughput, parallelized cytoindentor for local compression of live cells. The cytoindentor uses convex lens-induced confinement (CLiC) to indent micrometer-sized areas in single cells and/or populations of cells with submicron precision. This is accomplished using micropatterned poly(dimethylsiloxane) (PDMS) films that are adhered to a convex lens to create arrays of ext...