Certain fundamental principles are common to all distilling systems. Modern distillation systems are multi-stage, continuous, countercurrent, vapor-liquid contacting systems that operate within the physical laws that state that different materials boil at different temperatures. Represented in Figure 1 is a typical distillation tower that could be employed to separate an ideal mixture. Such a s...

A very simple way to improve the performance of almost any machine learning algorithm is to train many different models on the same data and then to average their predictions [3]. Unfortunately, making predictions using a whole ensemble of models is cumbersome and may be too computationally expensive to allow deployment to a large number of users, especially if the individual models are large n...

Architectural styles codify commonly used idioms in system structures, organizations, and interactions. Existing classifications of architectural styles provide empirical guidelines for style selection, but fail to systematically characterize styles or reveal their foundations. Moreover, the mapping between architectural styles and their implementations is generally poorly understood. This pape...

The promise of cardiac tissue engineering is in the ability to recapitulate in vitro the functional aspects of a healthy heart and disease pathology as well as to design replacement muscle for clinical therapy. Parts of this promise have been realized; others have not. In a meeting of scientists in this field, five central challenges or "big questions" were articulated that, if addressed, could...

Technologies for genome-wide sequence interrogation have dramatically improved our ability to identify loci associated with complex human disease. However, a chasm remains between correlations and causality that stems, in part, from a limiting theoretical framework derived from Mendelian genetics and an incomplete understanding of disease physiology. Here we propose a set of criteria, akin to K...

A procedure that enables the evaluation and further distillation of fixed pattern noise for digital capture devices is proposed. This method also allows for the direct calculation of the random, or temporal, noise contribution, devoid of fixed pattern components. Our method is consistent with a draft digital camera noise measurement standard under consideration through ISO 15739, but is intende...

The goal of prognostics and health management (PHM) systems is to ensure system safety, and reduce downtime and maintenance costs. It is important that a PHM system is verified and validated before it can be successfully deployed. Prognostics algorithms are integral parts of PHM systems. This paper investigates a systematic process of verification of such prognostics algorithms. To this end, fi...

Our aim is to contribute to biomedical text extraction and mining research. In this paper we present exploratory research on the MeSH terms assigned to MEDLINE citations. We analyze MeSH based co-occurrences and identify the interesting ones, i.e., those that are likely to be semantically meaningful. For each selected co-occurring pair we derive a weighted vector representation that emphasizes ...