An 8-year-old girl died of sepsis due to staphylococcal infection one year and 8 months after Bacille Calmette-Guerin (BCG) revaccination. Two months after the vaccination in accordance with the school health program, she was hospitalized with a high fever, skin rash over the face and lower limbs, and leukopenia. Her clinical and laboratory pictures were not compatible with those of any establi...

disseminated tuberculosis (tb) is commonly seen in hiv-infected patients and is major cause of death in these patients. in hiv-infected patients disseminated tuberculosis is frequently undiagnosed or misdiagnosed. in this article we report a case of disseminated tb in a hiv-infected patient with a relatively long history of fever and other complaints without definite diagnosis. diagnosis of dis...

conclusions combination therapy with surgical excision has a synergistic effect and appears to be the best treatment for extended lesions. however, new potent antibacterial drugs may help to improve the management of such infections when there are sufficient data on their in vitro activity. introduction nocardia species are described as opportunistic pathogens that mainly cause pulmonary nocard...

The pathologic findings from biopsy specimens from 9 patients with postvaccination bacille CalmetteGuérin (BCG) infection are presented. The patients were vaccinated with BCG during the first 2 days of life. Four patients had normal immunity and 5 patients were immunocompromised. The pathologic findings in both groups were different. Biopsy specimens from patients with normal immunity showed mu...

A patient with deep venous thrombosis and low protein S activity during the course of Salmonella typhimurium infection is presented. Although protein S deficiency has been reported in patients with disseminated intravascular coagulation, it was not present in this patient and his protein S activity was normal after the findings of infection and deep venous thrombosis disappeared.

Mycobacterium bovis BCG is one of the most commonly administered vaccines. Complications, including disseminated BCG disease, are rare but increasingly reported in immunodeficient children. There is growing recognition of the importance of differences between BCG vaccine strains. We determined the susceptibilities of five genetically distinct BCG vaccine strains to 12 antituberculous drugs.

Bacille Calmette-Guérin (BCG) vaccines are widely used, even though estimates of efficacy have ranged from zero to 80%. BCG is a relatively safe vaccine, but it can cause disseminated infection, especially in immunocompromised hosts. Thus, the development of a more reliably efficacious and safer vaccine is important to the control of tuberculosis. The testing of any new vaccine in human populat...