This article revisits the old controversy concerning the relation of the mother’s brother and sister’s son in patrilineal societies in the light both of anthropological criticisms of the very notion of kinship and of evolutionary and epidemiological approaches to culture. It argues that the ritualized patterns of behavior discussed by Radcliffe-Brown, Goody, and others are to be explained in te...

Five studies examined whether, in self-control dilemmas, individuals develop an implicit disposition to approach goals and avoid temptations, psychologically as well as physically. Using a method developed by A. K. Solarz (1960; see also K. L. Duckworth, J. A. Bargh, M. Garcia, & S. Chaiken, 2002), the authors assessed the time for pulling and pushing a lever in response to goal- and temptation...

The positive trend in volunteering among the Dutch young old may in part be due to a relatively favorable disposition to volunteer. Using data from the Longitudinal Aging Study Amsterdam, volunteering rates of 55-64 year olds in 1992 and 2002 were compared and associated with (among others) three types of dispositional factors: religious involvement, age-related engagement norms, and parental s...

Lanoteplase is a recombinant mutant of tissue-type plasminogen activator (t-PA) that was developed with an aim to overcome the drawback of rapid systemic elimination of t-PA. In this study, we examined the disposition profile of lanoteplase in vivo and the kinetics of receptor-mediated endocytosis (RME) of this recombinant t-PA in vitro to kinetically characterize the mechanism(s) underlying it...

Interruption of the neuraxis in the 'spinal cord injured' (SCI), brings about several pathophysiological changes in human body such as increase in total extracellular fluid volume, loss of venomotor tone. venopooling, and a change in the body adipose tissue consistency (1,2). To what extent these changes affect drug disposition kinetics and metabolism in the acute spinal man has not been clearl...

Disposition kinetics and urinary excretion of levofl oxacin was investigated after a single intravenous dose of 3 mg.kg-1 in male buffalo calves. The drug concentration was estimated in plasma and urine by microbiological assay using E. coli as the test organism. Disposition kinetic parameters were determined using a two-compartment open model and an appropriate dosage schedule was computed. Dr...

BACKGROUND Treatment of acute heart failure in the emergency department (ED) or observation unit is an alternative to hospitalization. Both ED management and observation unit management have been associated with reduced costs and may be used to avoid penalties related to rehospitalizations. The purpose of this study was to examine trends in ED visits for heart failure and disposition following ...