Colorectal cancer (CRC) is one of the leading causes of cancer deaths around the globe. Bioactive food ingredients such as prebiotics have protective potential in colon cancer. Data on galacto-oligosaccharides (GalOS) against CRC are very limited and GalOS used in this study have β-1,6 and β-1,3 as major glycosidic linkages and, to our best knowledge, were never used before against any cancer t...

In previous studies, we have isolated several marine indole alkaloids and evaluated them in the forced swim test (FST) and locomotor activity test, revealing their potential as antidepressant and sedative drug leads. Amongst the reported metabolites to display such activities was 5-bromo-N,N-dimethyltryptamine. Owing to the importance of the judicious introduction of halogens into drug candidat...

Worldwide, more than 230 million major surgical procedures are performed each year. For these patients, postoperative nausea and vomiting (PONV) are among the most frequently observed adverse events associated with the provision of general anaesthesia. It is distressing to patients and impairs the quality of recovery as judged by the patients and anaesthesiologists alike. 3 Our patients obvious...

A 10-year-old, 4.4 kg, intact female poodle presented with clinical signs of weakness in both hind limbs in May 2013 at the Veterinary Teaching Hospital, Kasetsart University, Bangkok, Thailand. The dog had a mild fever (39.5°C) and demonstrated hyperesthesia in the lumbar area. Radiographic imaging showed normal appearance of the spine and intervertebral disk spaces. A CBC was within reference...

s and the ICI Web of Science from November 1, 1999 to November 1, 2001. The literature search was augmented by consulting Analytical Abstracts, and the following journals publishing papers on TLC were searched directly: Journal of Chromatography (parts A and B and the bibliography issues), Journal of Chromatographic Science, Chromatographia, Analytical Chemistry, Journal of Liquid Chromatograph...

Seasickness or Mal de Mer is a very unpleasant experience, and most sailors, if all, had to cope with it. In its extreme form it leaves the victim unwilling to perform any task, even to assist in his or her own rescue. Motion sickness or cinetose is dependent on the magnitude of ship motion, but how it affects human operator is not unequivocal. We will review the different factors, environmenta...