نتایج جستجو برای: cycloguanil pamoate

تعداد نتایج: 304  

Journal: :Journal of wildlife diseases 2015
Timothy J Smyser Shylo R Johnson Melissa D Stallard Ashley K McGrew L Kristen Page Nikki Crider Lora R Ballweber Robert K Swihart Kurt C VerCauteren

Baylisascaris procyonis is a common gastrointestinal parasite of raccoons (Procyon lotor) and is a zoonotic helminth with the potential to cause severe or fatal infection. Raccoons thrive in human-dominated landscapes, and the fecal-oral transmission pathway and lack of effective treatment make B. procyonis a serious threat to public health. The distribution of medicinal baits has emerged as a ...

Journal: :The Journal of pharmacology and experimental therapeutics 2012
Laura Jenkins Nicholas Harries Jennifer E Lappin Amanda E MacKenzie Zaynab Neetoo-Isseljee Craig Southern Edward G McIver Stuart A Nicklin Debra L Taylor Graeme Milligan

Variation in pharmacology and function of ligands at species orthologs can be a confounding feature in understanding the biology and role of poorly characterized receptors. Substantial selectivity in potency of a number of GPR35 agonists has previously been demonstrated between human and rat orthologs of this G protein-coupled receptor. Via a bioluminescence resonance energy transfer-based assa...

2017
Timothy J. Smyser Shylo R. Johnson Melissa D. Stallard Ashley K. McGrew Kristen Page L. Kristen Page Nikki Crider Lora R. Ballweber Robert K. Swihart Kurt C. VerCauteren

Baylisascaris procyonis is a common gastrointestinal parasite of raccoons (Procyon lotor) and is a zoonotic helminth with the potential to cause severe or fatal infection. Raccoons thrive in human-dominated landscapes, and the fecal-oral transmission pathway and lack of effective treatment make B. procyonis a serious threat to public health. The distribution of medicinal baits has emerged as a ...

2017
Maxime G. Corral Julie Leroux Keith A. Stubbs Joshua S. Mylne

The evolutionary relationship between plants and the malarial parasite Plasmodium falciparum is well established and underscored by the P. falciparum apicoplast, an essential chloroplast-like organelle. As a result of this relationship, studies have demonstrated that herbicides active against plants are also active against P. falciparum and thus could act as antimalarial drug leads. Here we sho...

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