نتایج جستجو برای: convergence confinement method ccm
تعداد نتایج: 1726954 فیلتر نتایج به سال:
BACKGROUND AND PURPOSE The cerebral cavernous malformation (CCM) is a common and frequently unrecognized cause of stroke and epilepsy. It consists of blood-filled caverns lined by endothelial cells (EC) and devoid of mature vessel wall structure. Cultured EC obtained from CCM may express phenotypic and genotypic alterations contributing to CCM pathogenesis. We report the first successful isolat...
Cerebral cavernous malformations (CCMs) are vascular lesions of the central nervous system appearing as multicavernous, blood-filled capillaries, leading to headache, seizure and hemorrhagic stroke. CCM occurs either sporadically or as an autosomal dominant disorder caused by germline mutation of one of the three genes: CCM1/KRIT1, CCM2/MGC4607 and CCM3/PDCD10. Surgically resected human CCM les...
BACKGROUND Cardiac contractility modulation (CCM) signals are nonexcitatory electrical signals delivered during the absolute refractory period intended to improve contraction. We previously tested the safety and efficacy of CCM in 428 NYHA functional class III/IV heart failure patients with EF ≤35% and narrow QRS randomized to optimal medical treatment (OMT) plus CCM (n = 215) versus OMT alone ...
conclusions hemodialysis patients need a consistent care plan to manage poor sleep quality. this research has proven the effectiveness of implementing ccm as an intervention for improving the sleep quality of hemodialysis patients. ccm provides a comprehensive model for caring for hemodialysis patients, and its executive stages are congruent with the many stages of the nursing process. practiti...
The spontaneous dimerization of the frustrated spin-1 2 antiferromagnetic chains is studied by a microscopic approach based on a proper set of composite operators (i.e., pseudo-spin operators). Two approximation schemes are developed. Firstly, a spin-wave approximation is made by a Dyson-Maléev-like boson transformation. The ground-state properties and the triplet excitation spectra are obtaine...
Flanged shear walls are used extensively in moderate- and high-rise buildings to resist lateral loads induced by earthquakes. The seismic performance of many buildings is, therefore, closely linked to the behavior of the reinforced concrete walls. They must be carefully designed to provide not only adequate strength, but also sufficient ductility to avoid brittle failure under strong lateral lo...
BACKGROUND The Chronic Care Model (CCM) was developed to improve chronic disease care, but it may also inform delivery of other types of preventive care. Using hierarchical analyses of service delivery to patients, we explored associations of CCM implementation with diabetes care and counseling for diet or weight loss and physical activity in community-based primary care offices. METHODS Seco...
The fuel entropy and required drive energy for an inertial confinement fusion implosion are set by a sequence of shocks that must be precisely timed to achieve ignition. This Letter reports measurements of multiple spherical shock waves in liquid deuterium that facilitate timing inertial confinement fusion shocks to the required precision. These experiments produced the highest shock velocity o...
Three genetic mutations were found to cause cerebral cavernous malformation (CCM), a vascular anomaly predisposing affected individuals to hemorrhagic stroke. These CCM proteins function together as a protein complex in the cell. Loss of expression of each CCM gene results in loss of in vitro endothelial tube formation. Label-free differential protein expression analysis using multidimensional ...
Three genetic mutations were found to cause cerebral cavernous malformation (CCM), a vascular anomaly predisposing affected individuals to hemorrhagic stroke. These CCM proteins function together as a protein complex in the cell. Loss of expression of each CCM gene results in loss of in vitro endothelial tube formation. Label-free differential protein expression analysis using multidimensional ...
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