Colorectal masses can be non-neoplasm, benign neoplasm and malignant neoplasm. Diagnosis of colorectal mass done by biopsy or surgery then followed histopathological examination. The aim this study was to described the histopathology feature in Anatomic Pathology Laboratory Arifin Achmad Regional Hospital Riau Province January 2015 - December 2019. This found 304 cases consisted men (55,6%) wom...

Nasal cavity as the first site of metastases from colorectal adenocarcinoma without elsewhere is generally unheard and very rare with only a few cases reported in world literature. The diagnostic dilemma therapeutic challenge are significant when encountered clinical practice, especially to differentiate it primary nasal pathology. Histopathological examination immunohistochemistry play an impo...

Mucinous adenocarcinoma (MC) is a special histology subtype of colorectal adenocarcinoma. The survival of MC is controversial and the prognostic biomarkers of MC remain unclear. To analyze prognostic significance and molecular features of colorectal MC. This study included 755,682 and 1001 colorectal cancer (CRC) patients from Surveillance, Epidemiology, and End Results program (SEER, 1973-2011...

Thyroid transcription factor 1 (TTF-1) is considered a highly sensitive and specific marker for primary lung adenocarcinoma. However, in recent years retrospective studies of tumor samples have confirmed that, although rare, TTF-1 can also be expressed in colorectal adenocarcinoma. There are a few case reports of patients with TTF-1-positive colon adenocarcinoma in the medical literature but no...

BACKGROUND Calpains represent a well-conserved family of Ca2+ -dependent proteolytic enzymes. Recently, the importance of calpain in the metastatic process has received great attention. To investigate whether m-calpain contributes to the pathogenesis of colorectal cancer, we investigated the expression of m-calpain and its inhibitors, calpastatin and high-molecular-weight calmodulin-binding pro...

BACKGROUND 8-hydroxy-2'-deoxyguanosine (8-OHdG) is one of the most abundant oxidatively modified lesions in DNA and is a marker of the oxidative stress. 8-OHdG is a mutagenic lesion and it can mispair with adenine, causing G:C→T: A transversion. Our task was to determine the 8-OHdG level in patients with colorectal adenocarcinoma directly in tumor tissues and corresponding normal mucosa. MATE...

OBJECTIVE We reviewed cases of primary colorectal adenocarcinoma to document synchronous colon and rectum adenocarcinoma (SCRC). METHODS In a retrospective setting, 764 cases underwent surgical resection for primary colorectal adenocarcinoma and referred to the Department of Surgical Pathology, Uludag University, Medical Faculty for diagnoses between 1997 and 2006, were reviewed. Tumor site, ...

background : colorectal cancer, a major health concern worldwide, is the third most common form of cancer and second leading cause of cancer-related deaths. the flavonoids are naturally occurring diphenylpropanoids ubiquitous in plant foods and important components of the human diet. luteolin, a bioflavonoid, possesses many beneficial effects including antioxidant, anti-inflammatory, anti-aller...

BACKGROUND To define different prognostic groups of surgical colorectal adenocarcinoma patients derived from recursive partitioning analysis (RPA). METHODS Ten thousand four hundred ninety four patients with colorectal adenocarcinoma underwent colorectal resection from Taiwan Cancer Database during 2003 to 2005 were included in this study. Exclusion criteria included those patients with stage...

AIM To analyze vascular endothelial growth factor (VEGF), c-erbB-2 and c-erbB-3 expression and to evaluate their relation to clinicopathologic parameters and pathogenesis of colorectal carcinoma. METHODS Sections of adenoma, intramucosal carcinoma and adenocarcinoma were evaluated by immunohistochemistry in 85 malignant and 37 benign colorectal neoplasms for the expression of VEGF, c-erbB-2 a...