INTRODUCTION Posterior capsule opacification (PCO) is a visually-disabling complication of cataract surgery. OBJECTIVE To estimate energy levels for capsulotomy in various subtypes of PCO (membranous, fibrous and fibro-membranous). MATERIALS AND METHODS A total of 215 patients with PCO were randomly selected and evaluated for Nd: Yag laser capsulotomy, after a quiet post-operative course of...

OBJECTIVE  To compare the effectiveness of alternative first line treatment options for women with WHO group II anovulation wishing to conceive. DESIGN  Systematic review and network meta-analysis. DATA SOURCES  Cochrane Central Register of Controlled Trials, Medline, and Embase, up to 11 April 2016. STUDY SELECTION  Randomised controlled trials comparing eight ovulation induction treatme...

background: unovulation is the most common cause of infertility. the first line oral treatment has been clomiphene citrate. another anti-estrogen used for ovulation induction is tamoxifen. many unovulatory infertile women are resistance to anti-estrogens and need another treatment. alternative treatments are aromatas inhibitors. objective: this study was designed to compare the effectiveness of...

BACKGROUND The aim of this work was to evaluate the efficacy of adding dexamethazone (DEX) (high dose, short course) to clomiphene citrate (CC) in CC-resistant polycystic ovary syndrome (PCOS) with normal dehydroepiandrosterone sulphate (DHEAS) in induction of ovulation. METHODS Eighty infertile women with CC-resistant PCOS were randomly assigned into two groups. Group I: Clomiphene citrate 1...

OBJECTIVE To evaluate the effect of clomiphene in men with hypogonadism and conventionally treated nonfunctioning pituitary adenomas (NFPA). PATIENTS AND METHODS Open label, single-arm, prospective trial. Nine hypogonadal men (testosterone < 300 ng/dL and low/normal LH) with previously treated NFPA. Clomiphene (50 mg/day orally) for 12 weeks. Testosterone, estradiol, LH, FSH, prolactin and er...

In a double-blind clinical trial, 114 subfertile men were given courses of clomiphene citrate (100 mg daily for three 10-day periods in successive months) and ofplacebo tablets of identical appearance. There were no consistent changes in sperm density. No serious adverse reactions to clomiphene were seen. Further studies are recommended on the efficacy of clomiphene in doses of 25 to 50 mg dail...

polycystic ovary syndrom (pcos) is characterized by infertility, oligomenorrhea, and hyperandrogenism. clomiphene citrate (cc), an antiestrogen, is first-line treatment for pcos, if cc fails to induce ovulation, laparascopic electrocautery of the ovaries is offered. in this prospective controlled study, 52 women with clomiphen-resistant pcos (group 1) and 46 women with regular menstrual cycles ...

BACKGROUND Subfertility due to anovulation is a common problem in women. First-line oral treatment is with anti-oestrogens, for example clomiphene citrate, but resistance (failure to ovulate) may be apparent with clomiphene. Alternative and adjunctive treatments have been developed such as tamoxifen, dexamethasone, and bromocriptine. OBJECTIVES To determine the relative effectiveness of anti-...