OBJECTIVE To compare semen quality and levels of seminal oxidative stress among three groups: infertile men with varicocele, fertile men with varicocele, and healthy semen donors (controls) without varicocele. DESIGN Prospective study. SETTING Academic medical centers. INTERVENTION(S) None. PATIENT(S) Semen specimens were obtained from 21 infertile patients with varicocele, 15 fertile m...

INTRODUCTION It has been reported that varicocele might promote angiogenesis. However, it is not clearly identified how angiogenesis affect testicular morphology or spermatogenic activity. The objective of the study is to investigate the effect of spironolactone, as an angiogenesis inhibitor, on the ipsilateral testis morphology in left varicocele-induced rats. MATERIALS AND METHODS Twenty fo...

Varicocele isanabnormalenlargementof the internal spermatic vein and pampiniform plexus of the testis. Most urologists believe that varicoceles arise from incompetent or absence of valves within the major veins of the testis, although other etiological factors nodoubtplaya role [1].Varicocele typicallyoccurson the left side, but bilateral varicoceles occur in more than 50% of patients [2]. In t...

PURPOSE We determined whether varicocele treatment before intrauterine insemination significantly affects intrauterine insemination success rates. MATERIALS AND METHODS A total of 58 infertile couples, of whom the women had normal evaluations and men had abnormal semen analyses and a history of varicocele, were included in this study. They were identified after reviewing the charts of all wom...

Purpose of review Adolescent varicocele is a common lesion which remains poorly understood. Recent research in pathophysiology and surgical management has shed new light on this increasingly diagnosed clinical entity. Recent findings Recent research demonstrates the potential importance of heat and oxidative stress patterns on testicular dysfunction with varicocele. The importance of testicular...

BACKGROUND Present knowledge on the impact of varicoceles on testicular function is largely based on studies of subfertile and infertile men, making it difficult to extrapolate the impact of varicocele on the general population. OBJECTIVE To describe associations between varicocele and testicular function assessed by semen analysis and reproductive hormones in men from the general population....

In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain. The surgical treatment of varicocele for hypogonadism is controversial and debated. Recently, multiple reports in the literature have suggested that varicocele is associated with hypogonadism and varicocele repair can increase ...

Varicocele is the most common correctible cause of male infertility and is present in 15% to 20% of the male population. Despite its prevalence, the pathophysiology of varicocele remains under investigation. One of the largest obstacles in studying varicocele is that it is almost exclusively found in humans. This has necessitated the creation of an animal model of varicocele. The most commonly ...

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Dr. Rey, in his commentary (1), has provided us with a comprehensive summary of the practice recommendations proposed by Agarwal et al. (2) with additional discussion on the basic physiology of sperm DNA structure. The pros and cons of the eight available sperm DNA fragmentation (SDF) tests were listed by the author. ...