BACKGROUND Chronic liver disease is characterized by inflammation and fibrosis. As a consequence angiogenesis leading to new vasculature may have prognostic value in disease progression. Interfering with angiogenesis may be a potential target to avoid progression of liver disease. Hence we planned to evaluate the CD34 and vascular endothelial growth factor (VEGF), the markers for angiogenesis i...

context viral hepatitis and the consumption of alcohol are recognized as important reasons for the development of liver disease throughout the world. it would also seem that chronic alcoholism causes more severe and rapid progression of liver disease in patients with chronic hepatitis c, leading to more frequent liver cirrhosis and hepatocellular carcinoma. evidence acquisition the data for thi...

BACKGROUND & OBJECTIVES There are only a few studies on aetiology of portal hypertension among adults presenting to tertiary care centres in India; hence we conducted this study to assess the aetiological reasons for portal hypertension in adult patients attending a tertiary care centre in southern India. METHODS Causes of portal hypertension were studied in consecutive new adult patients wit...

The pediatric liver transplant evolved in the 1980s and became established in the 1990s. First successful pediatric liver transplant was performed in 1967 by Prof. Starlz. . There were rapid advances in adult transplantation throughout the 1970s. 1986, when most adult units claimed a 1 year survival rate of 80% average 1 year survival rates in children were only 60% (1). Since then, there have ...

Background/Aims Growth differentiation factor 15 (GDF-15) belongs to the transforming growth factor-β superfamily. GDF-15 is emerging as a biomarker for several diseases. The aim of this study was to determine the clinical performances of GDF-15 for the prediction of liver fibrosis and severity in chronic liver disease. Methods The serum GDF-15 levels were examined via enzyme immunoassay in 1...

BACKGROUND AND OBJECTIVES Assessing health-related quality of life is an important aspect of clinical practice. Thus, the present study attempts to assess the health-related quality of life of patients with chronic liver disease. METHODS A cross-sectional survey was conducted on 133 chronic liver disease patients, using three instruments: a demographic questionnaire, the Chronic Liver Disease...

background liver transplantation (lt) is the only treatment option for patients with advanced liver disease. currently, liver donation to these patients, considering priorities, is based on the model for end-stage liver disease (meld). meld score is a tool for predicting the risk of mortality in patients with advanced liver disease. however, few studies have so far been conducted in iran on the...

BACKGROUND AND AIMS The epidemiology of liver cirrhosis differs across sex, ethnic groups, and geographic regions. In 2000, chronic liver disease was the fifth leading cause of death in Mexico. Accurate knowledge of the demographics of liver disease is essential in formulating health-care policies. Our main aim was to project the trends in liver disease prevalence in Mexico from 2005 to 2050 ba...

Fever and thrombocytopenia mostly associated with dengue hemorrhagic fever. But on certain condition of fever thrombocytopenia, we still seek another etiology such as chronic liver disease. How to clarify between in