نتایج جستجو برای: cholinesterase celastrus paniculatus ros
تعداد نتایج: 35019 فیلتر نتایج به سال:
Cholinesterase inhibitors are the 'first-line' agents in the treatment of Alzheimer's disease. This article presents the latest information on their pharmacokinetic properties and pharmacodynamic activity. Tacrine was the first cholinesterase inhibitor approved by regulatory agencies, followed by donepezil, rivastigmine and recently galantamine. With the exception of low doses of tacrine, the c...
schizophrenia and various neurological disorders have some signs and symptoms. visual hallucinations are one of such disorders. the related studies in some diseases for example parkinson disease and lewy body dementia indicate that acetylcholine (ach) plays a significant role in neuropsychiatric manifestation and its association with visual hallucination; therefore, visual hallucinations occur ...
2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine carboxylate methyl chloride (AMO-1618) inhibits the activity of a cholinesterase isolated from mung bean (Phaseolus aureus) roots at concentrations comparable to those which retard growth and inhibit development of secondary roots of bean seedlings. Fifty per cent inhibition of the cholinesterase activity occurred at 0.21 mm. Inhibition of...
Cholinesterase Activity in Female Greenhouse Workers—Influence of Work Practices and Use of Oral Contraceptives: Jesper B NIELSEN, et al. Environmental Medicine, University of Southern Denmark—Objectives—Associations between serum butyryl cholinesterase activity in female greenhouse workers and information from a questionnaire on work, use of personal protective equipment, and lifestyle were ev...
A new sesquiterpene polyol ester with a beta-dihydroagarofuran skeleton, NW37 (1), and three known compounds NW13 (2), NW16 (3) and NW35 (4) were isolated by bioassay-guided fractionation from the highly polar MeOH extracts of the root bark of Celastrus angulatus. Their chemical structures were elucidated mainly by analyses of MS and NMR spectral data. The insecticidal activity of compound 1 ag...
People with genetic variants of cholinesterase respond abnormally to succinylcholine, experiencing substantial prolongation of muscle paralysis with apnea rather than the usual 2-6 min. The structure of usual cholinesterase has been determined including the complete amino acid and nucleotide sequence. This has allowed identification of altered amino acids and nucleotides. The variant most frequ...
The cholinesterase activity of the sera of 25 subjects diagnosed as homozygotes for the silent cholinesterase gene was studied by a sensitive enzymatic method employing several thiocholine esters and various inhibitors, and by disc electrophoretic, immunochemical, and chromatographic methods.(a) With one exception, the sera fell into two classes by all criteria. One class (type I, 16 cases) had...
Background We investigated the effect of cholinesterase inhibitors on all-cause discontinuation, efficacy and safety, and the effects of study design-, intervention-, and patient-related covariates on the risk-benefit of cholinesterase inhibitors for Alzheimer's disease. Methods A systematic review and meta-analysis of randomized placebo-controlled clinical trials comparing cholinesterase inh...
V,,,, and K,,, values with twenty-five “atypical” and thirty-seven “usual” cholinesterase human sera were determined for the cholinesterase substrates procaine, tetracaine, benzoylcholine, o-nitrophenylbutyrate, cu-naphthylacetate and aspirin. Aspirin was demonstrated to be a substrate for serum cholinesterase. For each of these substrates the ratio of V,,substrate to V,,,, benzoylcholine was f...
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