نتایج جستجو برای: carbopol 971

تعداد نتایج: 1574  

2014
Saleh A. Al-Suwayeh Ehab I. Taha Fahad M. Al-Qahtani Mahrous O. Ahmed Mohamed M. Badran

The current study was designed to develop a topical gel formulation for improved skin penetration of lornoxicam (LOR) for enhancement of its analgesic activity. Moreover, the effect of different penetration enhancers on LOR was studied. The LOR gel formulations were prepared by using hydroxylpropyl methylcellulose (HPMC) and carbopol. The carbopol gels in presence of propylene glycol (PG) and e...

2016
Cristina A. de Sousa-Lages Lívio P. de Deus-Lages Gabriela V. de Sousa Adinaide C. de Moura-Leal Airton Mendes Conde Danylo Rafhael Costa-Silva Maria da Conceição Barros-Oliveira Carine Soares Borges Carla Solange Escórcio-Dourado Fabiane A. Sampaio Lívio C. Cunha-Nunes Benedito B. da-Silva

OBJECTIVES To evaluate the effect of Carbopol gel formulations containing pilocarpine on the morphology and morphometry of the vaginal epithelium of castrated rats. METHODS Thirty-one female Wistar-Hannover rats were randomly divided into four groups: the control Groups I (n=7, rats in persistent estrus; positive controls) and II (n=7, castrated rats, negative controls) and the experimental G...

2010
HYDROCHLORIDE Swamy

Purpose of Study: In the present study, an attempt was made to design and evaluate buccoadhesive bilayer tablets of granisetron hydrochloride (an anti-emetic drug), in order to overcome bioavailability problems, to reduce dose dependent side effects and frequency of administration. Method: Bilayer buccal tablets containing the drug were prepared by direct compression method using combination of...

2012
Julia Hurler Nataša Škalko-Basnet

Chitosan is currently proposed to be one of the most promising polymers in wound dressing development. Our research focuses on its potential as a vehicle for nano-delivery systems destined for burn therapy. One of the most important features of wound dressing is its bioadhesion to the wounded site. We compared the bioadhesive properties of chitosan with those of Carbopol, a synthetic origin pol...

Journal: :Journal of ethnopharmacology 2009
Shila Gurung Natasa Skalko-Basnet

ETHNOPHARMACOLOGICAL RELEVANCE Carica papaya is traditionally used to treat various skin disorders, including wounds. It is widely used in developing countries as an effective and readily available treatment of various wounds, particularly burns. THE AIM OF THE STUDY This study was aimed at investigating the healing efficiency of papaya latex formulated as 1.0 and 2.5% hydrogels. MATERIALS ...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2009
Branka Ivić Svetlana Ibrić Gabriele Betz Zorica Djurić

The purpose of the study was to screen the effects of formulation factors on the in vitro release profile of diclofenac sodium from matrix pellets compressed into multiple unit pellet system (MUPS) tablets using design of experiment (DOE). Extended release of diclofenac sodium was accomplished using Carbopol 71G as matrix substance. According to Fractional Factorial Design FFD 2(3-1) four formu...

2013
Kirti Kumari Monika Sachdeva

A gel can be described as the cross-linked material that retains a large amount of solvent inside its medium and if the solvent retained is water, such material is known as hydrogel. Drug therapy of the inflammation of skin is mainly topical. This necessitates the treatment of symptoms, since in most cases causal treatment is impossible due to unknown etiology. Topical corticosteroids are the m...

2006
G. D. GUPTA R. S. GAUD

Tenoxicam is a nonsteroidal antiinflammatory drug, used in the treatment of inflammatory and degenerative disorders of the musculoskeletal system. It is from the oxicam group of nonsteroidal antiinflammatory agents. It is widely prescribed for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, extraarticular disorders, bursitis, tendonitis, and nonarticular rhe...

2012
Navneet Garud Akanksha Garud

Purpose: To prepare and evaluate metformin microspheres for prolonged release. Methods: Metformin microspheres were prepared by non-aqueous solvent evaporation method using various polymers, including ethylcellulose (EC), hydroxypropyl methylcellulose (HPMC), carbopol 934P (CA) and chitosan (CH). The effect of process variables, viz, drug/polymer ratio, stirring rate and type of polymer on the ...

2013
Asim.ur Rehman Gul M Khan Kifayat U Shah Shefaat U Shah Kamran A Khan

Purpose: To formulate and prepare controlled release (CR) matrix tablets of tramadol HCl using Carbopol 974P and 934 polymers as rate-controlling agents. Methods: The tablets were prepared by direct compression method using various drug to polymer (D:P) ratios. Co-excipients, including carboxymethylcellulose, starch and/or hydroxypropyl methylcellulose were also used to modulate the formulation...

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