نتایج جستجو برای: bone metabolism markers

تعداد نتایج: 724522  

2017
Yinqiu Yang Chenhe Zhao Jing Liang Mingxiang Yu Xinhua Qu

Diabetes mellitus has been demonstrated to be closely associated with osteoporosis. Accordingly, hypoglycemic therapy is considered effective in treating metabolic bone disease. Recently, the effects of dipeptidyl peptidase-4 (DPP-4) inhibitors, a new type of antidiabetic drug, on bone metabolism have been widely studied. This review mainly describes the effects of DPP-4 inhibitors on bone meta...

Journal: :Bone 2005
Karl J Obrant Kaisa K Ivaska Paul Gerdhem Sari L Alatalo Kim Pettersson H Kalervo Väänänen

In striving to refine the clinical utility of different markers of bone metabolism, we should take into account numerous confounders, many of which are well known, such as sampling time, fasting status, and bone density. One further confounder may be ongoing fracture healing and/or post-fracture immobilization, which at least theoretically should impose an increased bone formation and resorptio...

2013
Yoichi Aota Ko Ishida Nobuyuki Tanabe Tomoyuki Saito

Methods Using dual–energy X ray absorptiometry and bone metabolism markers (bone formation marker; BAP, bone resorption marker; TRAP5b), the bone mineral density of lumbar and bilateral proximal femurs were studied in 41 AIS patients aged 10 to 20 years old, with a mean of 15.2±5.9 years old. Divided into two groups by levels of bone resorption marker (TRAP5b), BMD, BMI and age of menarche were...

Journal: : 2022

Immune-mediated rheumatic diseases (IMRDs) are a broad group of pathological conditions based on impaired immunological tolerance to one’s own tissues leading inflammation and irreversible organ damage. Laboratory diagnosis IMRDs includes wide range biomarkers (autoantibodies, acute phase proteins, cytokines, markers endothelial damage, components the complement system, immunoglobulins, cryoglo...

Journal: :InterConf 2023

Rheumatoid arthritis (RA) is a systemic autoimmune disease with chronic inflammatory process that negatively affects bone metabolism, leading to violation of mineral density (BMD). Bone remodeling markers are important indicators the state tissue can provide additional information for clinician about BMD disorders. The patients were randomly enrolled in study preliminary stratification by prese...

2015
Ko Ishida Yoichi Aota Naoto Mitsugi Tomoyuki Katsuhata Takayuki Higashi Katsutaka Yamada Tomoyuki Saito

Methods Bone mineral density (BMD) of the lumbar spine and bilateral proximal femurs (dual energy x-ray absorptiometry) and bone metabolism markers {bone formation marker: serum bone alkaline phosphatase (BAP); bone resorption marker: serum tartrate-resistant acid phosphatase serum band 5 (TRAP5b)} were measured in 55 consecutive AIS subjects aged 10 to 18 years-old (mean: 15.6+/-1.7). BMD, bod...

2013
Eric Bonnet Jean-Bernard Ruidavets Anne Genoux Laurence Mabile Florian Busato Martine Obadia François Prévoteau Bruno Marchou Patrice Massip Fabrice Marion-Latard Cyrille Delpierre Jacques Bernard Bertrand Perret

BACKGROUND HIV-infected patients starting antiretroviral treatment (ART) experience deep and early disorders in fat and bone metabolism, leading to concomitant changes in fat mass and bone mineral density. METHODS We conducted a prospective study in treatment-naive HIV-infected patients randomized to receive two nucleoside reverse transcriptase inhibitors in combination with either a protease...

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