Screening of bioactive components is important for modernization and quality control of herbal medicines, while the traditional bioassay-guided phytochemical approach is time-consuming and laborious. The presented study proposes a strategy for rapid screening of active components from herbal medicines. As a case study, the quantitative pattern-activity relationship (QPAR) between compounds and ...

Various dietary components may modify chronic inflammatory processes at the stage of cytokine production, amplification of nuclear factor-kappaB-mediated inflammatory gene expression, and the release of anti-inflammatory cytokine, transforming growth factor-beta. This review provides a synopsis of the strengths and weaknesses of the evidence that specific bioactive food components influence inf...

India has rich history of using plants for medicinal purposes. Curcuma species are well-known indigenous medicine. They are used for the treatment of various ailments and metabolic disorders. In Manipur, traditionally the rhizomes of Curcuma caesia Roxb. is used in treating leucoderma, asthma, tumours, piles, bronchitis etc. The paste is applied on bruises, contusions and rheumatic pains. Essen...

Abutilon indicum Linn. is used in the treatment of various ailments either direct or in combination with other plants in many forms such as powder or liquid. This plant is the major source of various ayurvedic medicines, being made in ayurvedic pharmacies throughout the country. Looking the wider use of plant from the literature survey, it has been found that not much work has been carried out ...

Research into bioactive food compounds (BFC) continues to evolve albeit with shared challenges among scientists in the fields of obesity and cancer treatment and prevention. Given the diversity of scientific disciplines involved in evaluating BFC, multidisciplinary conferences provide opportunities to update the state of the science and critically discuss conceptual and methodological challenge...

Epigenetic processes participate in cancer development and likely influence cancer prevention. Global DNA hypomethylation, gene promoter hypermethylation and aberrant histone post-translational modifications are hallmarks of neoplastic cells which have been associated with genomic instability and altered gene expression. Because epigenetic deregulation occurs early in carcinogenesis and is pote...

Herbal medicine has been used to treat diseases for centuries; however, the biological active components and the mechanistic understanding of actions of plant-derived drugs are permanently discussed. MicroRNAs are a class of small, non-coding RNAs that play crucial roles as regulators of gene expression. In recent years, an increasing number of reports showed that microRNAs not only execute bio...