AIM To assess the cell mediated immune response to BCG vaccine in preterm babies. METHODS Sixty two consecutive preterm babies born at < 35 weeks of gestation were randomly allocated into two groups. Babies in group A were vaccinated early at 34-35 weeks and group B were vaccinated late at 38-40 weeks of postconceptional age. The two groups were similar in terms of: gestational age (mean (SD)...

Aim—To assess the cell mediated immune response to BCG vaccine in preterm babies. Methods—Sixty two consecutive preterm babies born at < 35 weeks of gestation were randomly allocated into two groups. Babies in group A were vaccinated early at 34–35 weeks and group B were vaccinated late at 38–40 weeks of postconceptional age. The two groups were similar in terms of: gestational age (mean (SD) 3...

BACKGROUND Epidemiologic data regarding tuberculin skin test (TST) responses are an important basis for TB control strategies. This study analyzed TST responses in Korea, which experienced a rapid change in BCG vaccination status. METHODS TST responses in young adults were examined over 5 years. Participants with active TB lesions were excluded. RESULTS A total of 5,552 participants were en...

AIM The aim of this study is to interpret purified protein derivative (PPD) induration sizes with respect to the number of Bacillus Calmette-Guérin (BCG) scars. METHODS We have considered 1879 school children between the ages of 7 and 14 years from seven primary schools in Kocaeli, Turkey. Children were injected with 5TU 0.1 mL PPD and induration sizes were measured at 72 h. Number of BCG sca...

BACKGROUND Mycobacterium bovis BCG vaccine has displayed inconsistent efficacy in different trials conducted in various geographical regions. Nevertheless, it significantly reduces the risk of severe childhood tuberculosis and continues to be used to prevent tuberculosis in many countries. Many studies revealed that efficacy of vaccine wanes with age. Most of the studies were based on in vivo a...

Hidradenomas are tumours that arise from the adnexal structures, both eccrine and apocrine and are histologically benign. The tumours that arise from eccrine differentiation are known as poroid hidradenomas and when they arise from the apocrine glands they are called nodular hidradenomas. In our centre a 13-year-old boy presented with a slow-growing, painless erythematous fungating nodule on th...

BACKGROUND To explore Bacillus Calmette-Guérin vaccine (BCG) as a protective factor against tuberculosis (TB) and how human immunodeficiency virus (HIV) infection modifies the effect of BCG on TB. METHODS Two matched case-control studies were conducted. One study compared TB cases and controls who were HIV positive. The second compared TB cases and controls who were HIV negative. The study po...

Background: Bacillus Calmette ET Guerin (BCG) vaccine, compulsory in endemic areas, remains the only available vaccine for prevention of Tuberculosis (TB) despite its modest protective value. Complications may arise in healthy/ immunocompromized hosts. Methods: Children presenting with BCG vaccine related complications in the form of local/distant complications were enrolled from 2007-2010 at C...

OBJECTIVES To determine treatment outcomes and associated predictors of all patients registered in 2012 with the Malaysian National Tuberculosis (TB) Surveillance Registry. METHODS Sociodemographic and clinical data were analysed. Unfavourable outcomes included treatment failure, transferred out and lost to follow-up, treatment defaulters, those not evaluated and all-cause mortality. RESULT...

Introduction: Tuberculosis remains a very important communicable disease in many parts of the world and major health problem developing countries. The international controversy surrounding use effectiveness Bacillus Calmette-Guérin vaccine. aim study is to evaluate spectrum tuberculosis among vaccinated non-vaccinated children’s. Method: A retrospective depending on data from flow sheet each pa...