SUPERFICIAL ocular infections, for example blepharitis, are better treated by local applications than by systemic therapy. Local applications of antibiotic and chemotherapeutic agents are also of value in reducing the incidence of infection after corneal injury. Sulphacetamide is most commonly used but, although its value in the prevention of corneal infection is well established (Cameron, 1949...

The incidence of multidrug-resistant (MDR) organisms, including methicillin-resistant Staphylococcus aureus (MRSA), is a serious threat to public health. Progress in developing new therapeutics is being outpaced by antibiotic resistance development, and alternative agents that rapidly permeabilize bacteria hold tremendous potential for treating MDR infections. A new class of glycopolymers inclu...

The vasoactive intestinal peptide (VIP) has been located in various structures of the rat brain, but few actions of the peptide have been reported as yet. Because VIP might interact with classical neurotransmitter systems in the central nervous system as it does in the periphery, we investigated whether VIP can modulate serotonin (5-HT1) receptors in membrane preparations obtained from brain ar...

SUPERFICIAL ocular infections, for example blepharitis, are better treated by local applications than by systemic therapy. Local applications of antibiotic and chemotherapeutic agents are also of value in reducing the incidence of infection after corneal injury. Sulphacetamide is most commonly used but, although its value in the prevention of corneal infection is well established (Cameron, 1949...