background: emergence of antimicrobial resistance toward a number of conventional antibiotics has triggered the search for antimicrobial agents from a variety of sources including the marine environment. objectives: the aim of this study was to evaluate the antimicrobial potential of holothuria leucospilota from qeshm and kharg islands against some selected bacteria and fungi. materials and met...

conclusions if medical treatment gets started early in the course of empyema, prognosis would be excellent. besides, there was no significant difference in short- and long-term outcomes between medical or surgical interventions. objectives the aim of this study was to compare the duration of admission, duration of intravenous antibiotic therapy, time to response to treatment, and outcomes of me...

Trichomonas vaginalis causes vaginitis and increases the risk of HIV transmission by heterosexual sex, while Tritrichomonas foetus causes premature abortion in cattle. Our goals were to determine the effects, if any, of anti-retroviral lectins, which are designed to prevent heterosexual transmission of HIV, on adherence of Trichomonas to ectocervical cells and on Tritrichomonas infections in a ...

The use of anti-tubercular therapy (ATT) along with anti-retroviral therapy (ART) in human immunodeficiency virus-tuberculosis (HIV-TB) co-infected individuals could at times lead to paradoxical worsening due to an increase in the inflammatory activity due to immune reconstitution inflammatory syndrome (IRIS) in the eye. This is characterized by anterior and posterior segment inflammatory react...

Immunogenic cancer therapies, including radiation and hypomethylating agents, such as 5-azacytidine, rely on tumor cell-intrinsic activation of the RNA receptor RIG-I for their synergism with immune checkpoint inhibitors. Possible ligands are small nuclear (snRNA) endogenous retroviral elements (ERV) leaking from nucleus during programmed cell death.

conclusions as a result of the full range uv-vis scanning of the responsible band in the hptlc experiments (200-700 nm), the flavonoid was the most imaginable natural compound. results through the bioassay guided fractionation method, the greatest antibacterial activities were related to the n-hexane extract. it was also revealed that the effective anti-mrsa agent of the assessed plant was a re...

background: the aim of this study was to compare the antibacterial efficacy of endemic satureja khuzistanica jamzad (skj) essential oil as root canal irrigation versus 2.5% sodium hypochlorite and 2% chlorhexidine gluconate.     methods: in current in vitro experimental study, fifty four single-rooted teeth were randomly divided into 6 groups of 9 samples: 2.5% sodium hypochlorite (naocl), 2% c...

background : prosthetic valve endocarditis (pve) is an important cause of morbidity and mortality associated with heart valve replacement surgery. the aim of the present study was to describe the early outcome of treatment in patients with pve in a single center. methods : the data of all the episodes of pve registered at our institution between 2002 and 2007 were collected and analyzed retrosp...