Chlorothalonil (tetrachloro-1,3-benzenedicarbonitrile, CAS 1897-45-6) is a pesticide that has been on the market for many years. It is used as a fungicide in agriculture, horticulture, and floriculture; as a wood preservative; and in paint. We report an epidemic of airborne irritant contact dermatitis, conjunctivitis, and upper airway complaints among seamstresses in a Portuguese trailer tent f...

This article reviews the international literature on the cost-effectiveness of immunotherapy for respiratory allergy. Included studies conducted an economic evaluation of immunotherapy for allergic rhinoconjunctivitis, allergic conjunctivitis, allergic rhinitis, asthma or allergic rhinitis in combination with asthma. Although there were few economic evaluations and these suffered from methodolo...

BACKGROUND The aim of this study was to compare patient-perceived relief of ocular itch, nasal symptoms, and eye drop comfort when allergic conjunctivitis was treated with bepotastine besilate 1.5% versus olopatadine hydrochloride 0.2%. METHODS This randomized, observer-masked, single-center, crossover study included 30 patients with ocular itching associated with allergic conjunctivitis acco...

BACKGROUND Symptom relief for the duration of 24 hours after treatment would benefit patients with allergic conjunctivitis. OBJECTIVE To compare the safety and efficacy of olopatadine 0.77% with vehicle or olopatadine 0.2% in patients with allergic conjunctivitis in a conjunctival allergen-challenge clinical study. PATIENTS AND METHODS In this Phase III, multicenter, double-masked, parallel...

The prevalence of allergic disease has been increasing over time and now represents a global health problem. For example, allergic disease in the UK affects up to 40% of children with allergic rhinitis accounting for a significant component of the allergic burden. There is also specific evidence for increasing prevalence of allergic rhinitis in the UK paediatric population, particularly among y...

Quantitative and qualitative disturbances in the composition of ocular surface microbiome can be a significant risk factor for development various ophthalmic disorders, including eyelid inflammation, dry eye syndrome, allergic conjunctivitis. In this publication, we present review data regarding association between dysbiosis these mentioned clinical conditions. Additionally, provide recommendat...