نتایج جستجو برای: acute myelocytic leukemia

تعداد نتایج: 688188  

Journal: :Blood 1984
B J Goodwin J O Moore J B Weinberg

Freshly isolated human leukemia cells have been shown in the past to display varying in vitro responses to phorbol diesters, depending on their cell type. Specific receptors for the phorbol diesters have been demonstrated on numerous different cells. This study was designed to characterize the receptors for phorbol diesters on leukemia cells freshly isolated from patients with different kinds o...

Journal: :Blood 2000
N Komatsu S Takeuchi T Ikezoe T Tasaka Y Hatta H Machida I K Williamson C R Bartram H P Koeffler H Taguchi

Mutations of coding repeats within the E2F4, TGF-betaRII, BAX, IGFIIR, and hMSH3 are critical targets of microsatellite instability (MSI) in many kinds of cancers. We analyzed 9 childhood acute lymphoblastic leukemia (ALL) samples, 5 acute myelocytic leukemia (AML) samples, and 10 adult T-cell leukemia (ATL) samples having MSI to determine whether they had mutations of the E2F4, TGF-betaRII, BA...

Journal: :Cancer research 1980
A Kessous P Colombies J Pris D Clement

This report describes a case of lymphoid blast crisis of a chronic myelocytic leukemia with the occurrence of a double chromosomal population carrying a Philadelphia chromosome. Fifty-five % of the cells have 28 chromosomes, and 36% show the exact duplicate of the near haploid chromosome complement. The similarities between this near haploid cell line and those previously reported, as well as t...

2005
Rainer Storb H. Joachim Deeg Lloyd Fisher Frederick Appelbaum C. Dean Buckner William Bensinger Reginald Clift Kristine Doney Claude Irle Robert McGuffin Paul Martin Jean Sanders Gary Schoch Jack Singer Patricia Stewart Keith Sullivan Robert Witherspoon

One hundred seventy-nine patients with acute nonlymphoblastic leukemia in first remission (n = 75). chronic myelocytic leukemia in chronic or accelerated phase (n = 48) or leukemia in advanced stage (n = 56) were given HLAidentical marrow grafts and randomized to receive methotrexate or cyclosporine for prevention of graftv-host disease (GVHD). The current report updates the three prospective t...

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