BACKGROUND Liver disease in pregnancy can have serious consequences. Its prevalence, profile and effect on outcome of pregnancy have not been documented systematically in India. We prospectively determined the frequency, causes and outcome of liver disease in pregnant women. SETTING Tertiary-care teaching hospital. METHODS Consecutive pregnant women with liver disease attending the inpatien...

context patients with hepatic dysfunction suffer from many problems and associated complications in organs other than the liver. therefore, it is very important to investigate the effects of different drugs in the treatment of these patients. due to the high consumption of non-steroidal anti-inflammatory drugs (nsaids), studying the effects of these drugs in patients with hepatic dysfunction is...

Renal complications are common in cirrhosis, especially in patients with refractory ascites, and they can negatively impact the patients’ survival. The International Ascites Club has set out clear diagnostic criteria for both acute and chronic forms of HRS. Nevertheless, IAC has not delineated guidelines for the diagnosis of other forms of renal impairment in cirrhosis, be they acute or chronic...

Abstract Mitochondrial fusion and fission, which are strongly related to normal mitochondrial function, referred as dynamics. defects in the liver cause a non-alcoholic steatohepatitis-like phenotype cancer. However, whether fission defect directly impair function stimulate disease progression, too, is unclear. Dynamin-related protein 1 (DRP1) key factor controlling fission. We hypothesized tha...

Background: Acute pancreatitis (AP) is a life-threatening disease. We aimed to explore the prognostic relevance of renal function based on estimated glomerular filtration rate (eGFR). Methods: A prospective registry AP patients was established by Hungarian Pancreatic Study Group. Data 1,224 consecutive were collected between 2012 and 2017. Patients divided into 3 groups according their eGFR mea...

A 37-year-old woman diagnosed with sickle cell anemia (SCA), beta (+) thalassemia, Crohn's disease, and liver dysfunction was scheduled for laparoscopic cholecystectomy (LC) due to acute cholecystitis with gall bladder. Regional anesthesia was performed. An epidural catheter was inserted into the 9-10 thoracal epidural space and then 15 ml of 0.5% bupivacaine was injected through the catheter. ...

PURPOSE OF REVIEW The incidence of cirrhosis is increasing exponentially and is associated with significant morbidity and mortality. This cirrhotic population is prone to infection, which is a frequent precipitant for the development of organ dysfunction; a syndrome often referred to as 'acute-on-chronic' liver failure. Historically, the perception of cirrhosis with organ dysfunction as having ...

background: renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. the aim of this study was to determine the final outcome of renal involvement in leptospirosis. methods: this longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. all patients we...

BACKGROUND The development of renal and liver dysfunction may be accompanied by initially subtle derangements in the gluconeogenetic function. Discrepantly low glucose levels combined with high lactate levels might indicate an impaired Cori cycle. Our objective was to examine the relation between early lactate and glucose levels with subsequent renal and liver dysfunction and hospital mortality...

methods fifty-three patients who were treated at the department of gastroenterology and hepatology of the university clinic essen from 2008 to 2013 included in this retrospective study. laboratory parameters were used to calculate non-invasive markers for liver fiibrosis. every patient underwent a liver biopsy within 6 months of the liver stiffness measurement. objectives autoimmune hepatitis (...