Interleukin 15 (IL-15) is a 14-15 kDa polypeptide that belongs to the 4 alpha-helix-bundle family of cytokines and was originally discovered due to its T cell proliferative activity. It utilizes the signal-transducing beta/gamma polypeptides of the IL-2 receptor complex, thus sharing many biological activities with IL-2, in addition to its high-affinity private receptor subunit IL-15R alpha. Ac...

Abdominal aort anevrizmalar (AAA)’da rüptür riski, öncelikle çapları ve artış miktarı ile orantılıdır. Literatürde rüptürediseke AAA’larda maksimum çapı >13 cm çok az vaka bildirilmiştir ve genel yaş ortalaması 70 yaş üzeridir. Çapları büyük olan AAA’larda cerrahi yaklaşım çok zor olmaktadır. Bazı durumlarda uygulanabilir tek tedavi şekli , başarılı sonuçları ile açık cerrahi anevrizma tamiri v...

A great advance in physics came when it was realized that it was better to think about motion in empty space rather than starting with what happen in the “real world” with gravity pulling things downwards, friction slowing things down, etc. First, that the laws of physics should be the same at one point as at another, i.e. that they are translation invariant, and also from one day to another, i...

The effect of incision length on patient recovery following cholecystectomy has not been investigated previously. In this study, 30 patients with symptomatic gallstones were randomized to cholecystectomy through a 6 cm or 15 cm transverse subcostal incision. Postoperative hospital stay was significantly shorter in the 6 cm incision group (median 3 days vs 5 days; P = 0.0069 Mann-Whitney U-test)...