Some cruciferous plants may serve as preventive treatments for several medical conditions; our objective was to systematically investigate their safety in humans. Four electronic databases were searched, and, of 10,831 references identified, 50 were included. Data were extracted by two independent reviewers, whereafter the association between interventions and adverse events was assessed. Adver...

Saahil Mehta, Prokar Dasgupta and Ben J. Challacombe, The Urology Centre, Guy’s Hospital, London This article was originally published in BJU Int 2010;106:1247–8. The rapid dissemination of roboticassisted laparoscopic surgery into surgical practice over the past five years has been startling. Urology has been quick to develop robotic-assisted techniques, particularly in the treatment of locali...

In this paper, we examine factors associated with poor pregnancy outcomes among teenagers in South Nyanza region of Kenya. The analysis is based on a recent WHO funded study on Adolescent safe motherhood in the region, which involved a survey of 1247 adolescents aged 12-19 and in-depth interviews with 39 of the adolescents who had experienced very early pregnancies or a pregnancy wastage. The i...

1 Mahler DA, Huang S, Tabrizi M, et al. Efficacy and safety of a monoclonal antibody recognizing interleukin-8 in COPD: a pilot study. Chest 2004; 126:926–934 2 De Boer WI. Cytokines and therapy in COPD: a promising combination? Chest 2002; 121:209S–218S 3 Barnes PJ, Hansel TT. Prospects for new drugs for chronic obstructive pulmonary disease. Lancet 2004; 364:985–996 4 Tsoumakidou M, Tzanakis ...

TABLE OF CONTENTS INTRODUCTION: LAWS TARGETING PRICE DISCRIMINATION .............. 1237 I. ECONOMIC CONCEPTIONS OF PRICE DISCRIMINATION: A BRIEF REVIEW ..................................................................... 1239 A. Price Discrimination, Defined .......................................... 1239 B. Arbitrage, Market Power, and Price Discrimination ........ 1243 C. Price Discriminatio...

We investigate the issue of implementation via individually rational ex-post budget-balanced Bayesian mechanisms. We show that all decision rules generating a nonnegative expected social surplus are implementable via such mechanisms if and only if the probability distribution of the agents’ type profiles satisfies two conditions: the well-known condition of Crémer and McLean [1988. Full extract...

While we were characterizing Cdi4 and its interaction with cyclin E, two groups, one led by de Nooij and Hariharan and the other by Lane and Lehner, independently isolated mutations in a gene, decapo, that encodes Cdi4. Both groups presented elegant experiments demonstrating the importance of decapo in regulating the cell cycle during development (de Nooij et al., 1996. Cell 87, 1237-1247 [Medl...

We studied the population genetic structure of 360 and 1247 adult Schistosoma mansoni using seven microsatellite and seven random amplified polymorphic DNA (RAPD) markers, respectively. Parasites were collected from their natural definitive host Rattus rattus in Guadeloupe (West Indies). We found a sex-specific genetic structure, a pattern never before reported in a parasitic organism. Male gen...

We report a continuous-wave (cw) source of tunable radiation across 333-345 nm in the ultraviolet (UV) using bismuth triborate, BiB₃O₆ (BIBO) as the nonlinear gain material. The source is based on internal sum-frequency-generation (SFG) in a cw singly-resonant optical parametric oscillator (OPO) pumped at 532 nm. The compact tunable source employs a 30-mm-long MgO:sPPLT crystal as the OPO gain ...

The forkhead box P2 gene, designated FOXP2, is the first gene implicated in a speech and language disorder. Since its discovery, many studies have been carried out in an attempt to explain the mechanism by which it influences these characteristically human traits. This review presents the story of the discovery of the FOXP2 gene, including early studies of the phenotypic implications of a disru...