The effects of whole green tea infusion on mouse urinary bladder chemical carcinogenesis

نویسندگان

  • Ana I Faustino-Rocha Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • Ana MVD Ferreira Chemistry Research Center, CQ-VR, University of Trás-os-Montes and Alto Douro, 5001-801, Vila Real, Portugal
  • Andreia Andrade Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • Andreia Henriques Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • Bruno Colaço Department of Zootechnics, University of Trás-os-Montes and Alto Douro, 911 Vila Real, Portugal Center for the Study of Animal Sciences (CECA), University of Porto, 4485-661, Porto, PortugalCentre for the Research and Technology
  • Catarina I Teixeira-Guedes Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • Daniela Talhada Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • Fernando M Nunes Chemistry Research Center, CQ-VR, University of Trás-os-Montes and Alto Douro, 5001-801, Vila Real, Portugal
  • Jacinta Pinho-Oliveira Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • José H Teixeira Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • Maria J Pires Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, PortugalCenter for the Study of Animal Sciences (CECA), University of Porto, 4485-661, Porto, PortugalCentre for the Research and Technology
  • Maria N Paiva-Cardoso Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
  • Paula A Oliveira Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, PortugalCenter for the Study of Animal Sciences (CECA), University of Porto, 4485-661, Porto, PortugalCentre for the Research and Technology
  • Regina Arantes-Rodrigues Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal
چکیده مقاله:

Objective(s):Green tea (GT) is one of the most popular beverages worldwide whose beneficial effects on health have been demonstrated. Recent studies suggest that GT may contribute to reduction of cancer risk and progression. The aim of this study was to evaluate the effects of whole GT on urinary bladder chemical carcinogenesis in male and female ICR mice. Materials and Methods: The GT characterization was performed using spectrophotometric methods. Urinary bladder lesions were induced using N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) by gavage during 10 weeks and whole GT (0.5%) was provided ad libitum during 20 weeks. Results:Animals from groups BBN+GT and BBN only developed preneoplastic lesions. Conclusion:We did not observe any effects by GT infusion administration on urinary bladder cancer development.

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عنوان ژورنال

دوره 17  شماره 2

صفحات  145- 148

تاریخ انتشار 2014-02-01

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