The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats

نویسندگان

  • Aydan Caglayan Hacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 Turkey
  • Belma Kocer-Gumusel Hacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 Turkey
  • Filiz Hincal Hacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 Turkey
  • Pinar Erkekoglu Hacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 Turkey
چکیده مقاله:

Objective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. This study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme activities in the presence of iodine and/or selenium deficiency on a rat model. Materials and Methods: Iodine and/or selenium deficiency was induced by feeding  three-week-old Wistar rats with a diet containing

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منابع مشابه

the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats

objective(s): particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. this study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme act...

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عنوان ژورنال

دوره 19  شماره 10

صفحات  1040- 1048

تاریخ انتشار 2016-10-01

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