The effect of green tea extract on oxidative stress and spatial learning in Streptozotocin-diabetic rats
نویسندگان
چکیده مقاله:
Diabetes mellitus is associated with distribution of cognitive functioning. Hyperglycemia Diabetes mellitus is associated with distribution of cognitive functioning. Hyperglycemia induced oxidative stress has been proposed as a cause of memory complications of diabetes including cognitive impairment. The aim of this study was to examine total green tea extract (TGTE), a potent free radical scavenger against spatial impairment in Streptozotocin-diabetic rats. Eight weeks after diabetes induction, TGTE was administrated in drinking water 3mg/L. The learning and memory behavior was evaluated with Morris water maze task in male rats. Then for estimation of oxidative stress parameters such as lipid peroxidation (LPO), total antioxidant capacity (FRAP) and total thiol groups in blood were scarified. The total green tea extract showed improved cognitive impairment in diabetic groups but these changes weren’t significant. There was also significant increase FRAP level and total thiol groups in treated green tea groups vs. control. group. This study demonstrated the effectiveness of TGTE on spatial impairment and oxidative stress induced in diabetes mellitus.
منابع مشابه
The Effect of Green Tea Extract on Oxidative Stress and Spatial Learning in Streptozotocin-diabetic Rats
Diabetes mellitus is associated with distribution of cognitive functioning. Hyperglycemia induced oxidative stress has been proposed as a cause of memory complications of diabetes including cognitive impairment. The aim of this study was to examine total green tea extract (TGTE), a potent free radical scavenger against spatial impairment in Streptozotocin-diabetic rats. Eight weeks after diabet...
متن کاملthe effect of green tea extract on oxidative stress and spatial learning in streptozotocin-diabetic rats
diabetes mellitus is associated with distribution of cognitive functioning. hyperglycemia diabetes mellitus is associated with distribution of cognitive functioning. hyperglycemia induced oxidative stress has been proposed as a cause of memory complications of diabetes including cognitive impairment. the aim of this study was to examine total green tea extract (tgte), a potent free radical scav...
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15 صفحه اولEvaluation of anti-diabetic effects of hydroalcoholic extract of green tea and cinnamon on streptozotocin-induced diabetic rats
Today diabetes is one of the most common diseases in the world that affects half of the world population. The use of medicinal herbs especially green tea and cinnamon has been taken into consideration for relieving the symptoms of diabetes, but there were some different ideas about their effectiveness. So, this study was conducted to evaluate the effect of cinnamon and green tea extract, indivi...
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عنوان ژورنال
دوره 16 شماره 1
صفحات 201- 209
تاریخ انتشار 2017-03-01
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